HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~Xpo1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0019904 - protein domain specific binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1071 Hs			1 238
+	Xl
		1237707 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q7ZWX7_XENLA (1-98): 1.17e-34: 124: 63.27
+	Hs
		173131 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PPIL4_HUMAN (1-84): 1.76e-25: 105: 26.97
+	Hs
		172600 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NCBP2_HUMAN (10-114): 8.11e-26: 100: 23.42
+	Hs
		172408 XPO1_HUMAN (1-1071): 0: 1022: 100.00		HNRPC_HUMAN (3-186): 3.01e-24: 99: 22.58
+	Hs
		172774 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PABP4_HUMAN (6-163): 5.37e-21: 93.2: 16.15
+	Hs
		172735 XPO1_HUMAN (1-1071): 0: 1022: 100.00		SRSF1_HUMAN (10-81): 4.53e-21: 90.3: 48.65
+	Hs
		172438 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PABP1_HUMAN (6-96): 2.86e-19: 88.2: 22.34
+	Hs
		172884 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PAP1L_HUMAN (6-96): 3.05e-19: 87.8: 23.40
+	Hs
		172707 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TIAR_HUMAN (5-97): 5.71e-16: 77.8: 25.51
+	Hs
		173306 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RBM4_HUMAN (12-89): 4.46e-14: 72.2: 33.33
+	Xl
		1237786 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		EPABA_XENLA (1-95): 1.14e-18: 86.3: 24.00
+	Xl
		1225285 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q640I0_XENLA (12-89): 5.7e-13: 69.1: 33.33
+	Sc
		403399 XPO1_YEAST (14-1067): 0: 848: 46.08		PABP_YEAST (7-95): 4.38e-17: 81.7: 22.34
+	Hs
		1336769 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		RB15B_HUMAN (4-232): 1.78e-31: 123: 22.41
+	Mm
		1296923 XPO7_MOUSE (23-1013): 5.45e-120: 397: 13.01		SRSF7_MOUSE (8-238): 6.46e-29: 111: 97.40
+	Mm
		1423638 XPO7_MOUSE (23-1013): 5.45e-120: 397: 13.01		NCBP2_MOUSE (10-114): 1.8e-25: 99.5: 23.42
+	Mm
		1016705 XPO7_MOUSE (23-1013): 5.45e-120: 397: 13.01		SRSF3_MOUSE (5-154): 2.54e-24: 96.5: 55.33
+	Mm
		1243946 XPO7_MOUSE (23-1013): 5.45e-120: 397: 13.01		SRSF1_MOUSE (10-81): 4.53e-21: 90.3: 48.65
+	At
		1298926 MOS14_ARATH (26-1002): 6.4e-104: 350: 13.35		RSZ33_ARATH (1-229): 5.09e-28: 109: 34.18
+	At
		307119 MOS14_ARATH (26-1002): 6.4e-104: 350: 13.35		RSZ21_ARATH (11-212): 1.31e-26: 103: 37.13