Protein: KLH15
Kelch-like protein 15

Gene: KLH15, KLHL15
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q96M94

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0071630 - nuclear protein quality control by the ubiquitin-proteasome system

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042306

CUL3
Cullin-3

7

20

Small-scale

0.963

High

1274019

CUL5
Cullin-5

1

20

High-throughput

0.691

High

1297681

KLH13
Kelch-like protein 13

1

19

High-throughput

0.691

High

1184943

CSN6
COP9 signalosome complex subunit 6

3

10

High-throughput

0.671

High

1189171

SAMD7
Sterile alpha motif domain-containing protein 7

3

1

High-throughput

0.667

High

1297672

CTIP
DNA endonuclease RBBP8

3

0

Small-scale

0.659

High

1239394

ZN511
Zinc finger protein 511

3

0

High-throughput

0.638

High

1288947

PBIR1
PPP2R1A-PPP2R2A-interacting phosphatase regulator 1

3

0

High-throughput

0.638

High

1281616

RNF34
E3 ubiquitin-protein ligase RNF34

2

1

High-throughput

0.628

High

1272543

CSN5
COP9 signalosome complex subunit 5

2

11

High-throughput

0.621

High

1297680

KLH14
Kelch-like protein 14

1

19

High-throughput

0.618

High

1297669

KLH15
Kelch-like protein 15

1

19

Small-scale

0.618

High

1229755

ZN444
Zinc finger protein 444

2

5

High-throughput

0.611

High

1297683

CSN3
COP9 signalosome complex subunit 3

2

15

High-throughput

0.611

High

606928

IDS
Iduronate 2-sulfatase

3

1

High-throughput

0.609

High

1102082

CB068
UPF0561 protein C2orf68

3

1

High-throughput

0.609

High

1127676

PRC2B
Protein PRRC2B

3

2

High-throughput

0.609

High

1297682

WRP73
WD repeat-containing protein WRAP73

3

2

High-throughput

0.609

High

439252

MMP2
72 kDa type IV collagenase

2

0

High-throughput

0.602

High

1012065

ELP6
Elongator complex protein 6

2

0

High-throughput

0.602

High

1128007

TOIP1
Torsin-1A-interacting protein 1

2

0

High-throughput

0.602

High

1157596

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.602

High

1255783

ELP5
Elongator complex protein 5

2

0

High-throughput

0.602

High

1297670

DMRTB
Doublesex- and mab-3-related transcription factor B1

2

0

High-throughput

0.602

High

1297684

LIMC1
LIM and calponin homology domains-containing protein 1

3

1

High-throughput

0.599

High

56486

FRMD3
FERM domain-containing protein 3

2

3

High-throughput

0.574

High

601799

CD72
B-cell differentiation antigen CD72

2

2

High-throughput

0.574

High

1217424

NUDC3
NudC domain-containing protein 3

2

20

High-throughput

0.558

High

49195

TLDC2
TLD domain-containing protein 2

1

1

High-throughput

0.536

High

235572

VINEX
Vinexin

1

2

High-throughput

0.536

High

1070597

RNPS1
RNA-binding protein with serine-rich domain 1

1

1

High-throughput

0.536

High

1079579

NEDD8
NEDD8

1

3

High-throughput

0.536

High

1263344

CSN9
COP9 signalosome complex subunit 9

1

1

High-throughput

0.536

High

1292374

DCNL1
DCN1-like protein 1

1

10

High-throughput

0.536

High

923756

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.513

High

1237541

ZN366
Zinc finger protein 366

1

0

High-throughput

0.513

High

1297673

SOSB1
SOSS complex subunit B1

1

0

High-throughput

0.513

High

1297679

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.513

High

1297686

MTL5
Tesmin

1

0

High-throughput

0.513

High

62830

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

1

1

High-throughput

0.489

High

204722

E41L2
Band 4.1-like protein 2

1

3

High-throughput

0.489

High

1059129

ICAM4
Intercellular adhesion molecule 4

1

2

High-throughput

0.489

High

1077635

KISS1
Metastasis-suppressor KiSS-1

1

3

High-throughput

0.489

High

1219518

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.489

High

1245471

GP150
Probable G-protein coupled receptor 150

1

1

High-throughput

0.489

High

1297675

RFIP5
Rab11 family-interacting protein 5

1

1

High-throughput

0.489

High

432161

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

438437

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

921393

RBX1
E3 ubiquitin-protein ligase RBX1

1

7

Small-scale

0.479

High

930963

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

1

Small-scale

0.479

High

1297687

ARI1
E3 ubiquitin-protein ligase ARIH1

1

13

High-throughput

0.479

High

166598

DCLK1
Serine/threonine-protein kinase DCLK1

1

5

Small-scale

0.470

High

1044325

FCL
GDP-L-fucose synthase

1

2

High-throughput

0.470

High

1234194

DCLK2
Serine/threonine-protein kinase DCLK2

1

6

Small-scale

0.470

High

672247

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

Small-scale

0.458

High

208285

DCX
Neuronal migration protein doublecortin

1

3

Small-scale

0.437

High

721190

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1242634

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

3

High-throughput

0.437

High

1297674

LZTS2
Leucine zipper putative tumor suppressor 2

1

7

High-throughput

0.437

High

1297677

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1297685

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

3

High-throughput

0.437

High

323520

CER1
Cerberus

3

0

High-throughput

0.347

High

532353

PPA5
Tartrate-resistant acid phosphatase type 5

3

0

High-throughput

0.347

High

1297676

BORG4
Cdc42 effector protein 4

3

0

High-throughput

0.347

High

1297688

KPTN
KICSTOR complex protein kaptin

3

0

High-throughput

0.347

High

1144607

TENS2
Tensin-2

2

0

High-throughput

0.331

High

351611

COLI
Pro-opiomelanocortin

2

0

High-throughput

0.328

High

812799

CASA1
Alpha-S1-casein [Cleaved into: Casoxin-D]

2

0

High-throughput

0.328

High

971944

CACB1
Voltage-dependent L-type calcium channel subunit beta-1

2

0

High-throughput

0.328

High

1109761

CC50B
Cell cycle control protein 50B

2

0

High-throughput

0.328

High

1297671

F161B
Protein FAM161B

2

0

High-throughput

0.328

High

1297678

PAAT
ATPase PAAT

2

0

High-throughput

0.328

High

958749

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

Small-scale

0.292

High

806634

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.279

Low

1085215

PRSS8
Prostasin

1

0

High-throughput

0.279

Low

1231057

THEM5
Acyl-coenzyme A thioesterase THEM5

1

0

High-throughput

0.279

Low

1235107

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.279

Low

1251834

F110D
Protein FAM110D

1

0

High-throughput

0.279

Low

1259427

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.279

Low

1295568

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024