Protein: RB15B
Putative RNA-binding protein 15B (One-twenty two protein 3) (HsOTT3) (HuOTT3) (RNA-binding motif protein 15B)

Gene: RB15B, RBM15B
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q8NDT2

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0001510 - RNA methylation
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1336751

RBM15
RNA-binding protein 15

3

17

Small-scale

0.861

High

1290596

ZCH18
Zinc finger CCCH domain-containing protein 18

3

7

High-throughput

0.667

High

1006563

SRPK2
SRSF protein kinase 2

1

16

High-throughput

0.647

High

1336752

WDR83
WD repeat domain-containing protein 83

4

7

High-throughput

0.630

High

783339

TRI23
E3 ubiquitin-protein ligase TRIM23

2

3

High-throughput

0.628

High

1199597

KLH22
Kelch-like protein 22

2

3

High-throughput

0.628

High

1336763

SPN90
NCK-interacting protein with SH3 domain

2

1

High-throughput

0.628

High

401162

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

10

High-throughput

0.618

High

472902

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

17

High-throughput

0.618

High

485275

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

High-throughput

0.618

High

877176

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.618

High

897904

CDK9
Cyclin-dependent kinase 9

1

15

High-throughput

0.618

High

1132837

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

10

High-throughput

0.618

High

1148523

SF3B4
Splicing factor 3B subunit 4

1

16

High-throughput

0.618

High

1290079

THOC4
THO complex subunit 4

1

15

Small-scale

0.618

High

1336741

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

1

High-throughput

0.618

High

1336767

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.618

High

1336768

KDM5B
Lysine-specific demethylase 5B

1

3

Small-scale

0.618

High

1145495

RBBP5
Retinoblastoma-binding protein 5

2

8

High-throughput

0.611

High

1336753

REPI1
DNA-binding protein REPIN1

2

0

High-throughput

0.602

High

966633

1433G
14-3-3 protein gamma

2

13

High-throughput

0.601

High

1336750

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

High-throughput

0.586

High

410949

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

5

High-throughput

0.576

High

1278542

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

1

High-throughput

0.574

High

1308807

NAV2
Neuron navigator 2

1

5

High-throughput

0.573

High

1336770

CDC23
Cell division cycle protein 23 homolog

1

5

High-throughput

0.573

High

396537

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1336765

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

2

Small-scale

0.571

High

1336766

NXF1
Nuclear RNA export factor 1

1

4

Small-scale

0.561

High

1049575

1433F
14-3-3 protein eta

2

13

High-throughput

0.549

High

538436

EGR2
E3 SUMO-protein ligase EGR2

1

1

High-throughput

0.541

High

251627

CCNT1
Cyclin-T1

1

6

High-throughput

0.536

High

846387

MATR3
Matrin-3

1

8

High-throughput

0.536

High

1023578

CYC
Cytochrome c

1

1

High-throughput

0.536

High

1117605

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.536

High

1136042

CND2
Condensin complex subunit 2

1

2

High-throughput

0.536

High

1136469

FL2D
Pre-mRNA-splicing regulator WTAP

1

2

High-throughput

0.536

High

1229569

VIR
Protein virilizer homolog

1

2

High-throughput

0.536

High

1287858

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

3

High-throughput

0.536

High

1336744

EZH1
Histone-lysine N-methyltransferase EZH1

1

7

High-throughput

0.536

High

158660

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.513

High

948559

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1336748

THOC1
THO complex subunit 1

1

0

High-throughput

0.513

High

993920

TNNC1
Troponin C, slow skeletal and cardiac muscles

1

1

High-throughput

0.494

High

1336754

TRI54
Tripartite motif-containing protein 54

1

19

High-throughput

0.494

High

302900

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

6

High-throughput

0.489

High

1128924

I13R2
Interleukin-13 receptor subunit alpha-2

1

2

High-throughput

0.489

High

1336742

JPH3
Junctophilin-3

1

1

High-throughput

0.489

High

1336746

ARRD3
Arrestin domain-containing protein 3

1

6

High-throughput

0.489

High

1336771

ANR50
Ankyrin repeat domain-containing protein 50

1

1

High-throughput

0.489

High

1336774

CEP83
Centrosomal protein of 83 kDa

1

6

High-throughput

0.489

High

217487

E41L2
Band 4.1-like protein 2

1

3

High-throughput

0.479

High

252257

CCNT2
Cyclin-T2

1

6

High-throughput

0.479

High

318515

TOX4
TOX high mobility group box family member 4

1

10

High-throughput

0.479

High

372608

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.479

High

406402

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.479

High

425573

ISG15
Ubiquitin-like protein ISG15

1

10

High-throughput

0.479

High

731473

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.479

High

904939

MECP2
Methyl-CpG-binding protein 2

1

6

High-throughput

0.479

High

928494

TERF1
Telomeric repeat-binding factor 1

1

3

High-throughput

0.479

High

980007

H4
Histone H4

1

4

High-throughput

0.479

High

1024706

VIGLN
Vigilin

1

20

High-throughput

0.479

High

1107030

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1137397

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1149937

TERF2
Telomeric repeat-binding factor 2

1

3

High-throughput

0.479

High

1250015

WDR82
WD repeat-containing protein 82

1

13

High-throughput

0.479

High

1271741

MEPCE
7SK snRNA methylphosphate capping enzyme

1

5

High-throughput

0.479

High

1277862

NUFP2
FMR1-interacting protein NUFIP2

1

3

High-throughput

0.479

High

1294091

DDX42
ATP-dependent RNA helicase DDX42

1

10

High-throughput

0.479

High

1313268

SMC5
Structural maintenance of chromosomes protein 5

1

9

High-throughput

0.479

High

1336739

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.479

High

1336740

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

1336743

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1336755

NSRP1
Nuclear speckle splicing regulatory protein 1

1

2

High-throughput

0.479

High

1336757

SENP2
Sentrin-specific protease 2

1

3

High-throughput

0.479

High

1336758

ANLN
Anillin

1

7

High-throughput

0.479

High

1336759

RAD18
E3 ubiquitin-protein ligase RAD18

1

2

High-throughput

0.479

High

1336761

DDX56
Probable ATP-dependent RNA helicase DDX56

1

19

High-throughput

0.479

High

1336769

XPO7
Exportin-7

1

7

High-throughput

0.479

High

301576

WFS1
Wolframin

1

1

High-throughput

0.470

High

675592

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

954718

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.458

High

1004851

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1205073

FA76B
Protein FAM76B

1

0

High-throughput

0.458

High

138229

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

6

High-throughput

0.457

High

686285

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.445

High

1327321

ZN276
Zinc finger protein 276

1

2

High-throughput

0.445

High

1336773

LC7L2
Putative RNA-binding protein Luc7-like 2

1

7

High-throughput

0.445

High

412276

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.437

High

1124657

SRC8
Src substrate cortactin

1

4

High-throughput

0.437

High

1134993

CUL7
Cullin-7

1

8

High-throughput

0.437

High

1227079

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.437

High

1254701

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

1336764

HECW2
E3 ubiquitin-protein ligase HECW2

1

6

High-throughput

0.437

High

1336772

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

High-throughput

0.437

High

1336738

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.426

High

49169

POTB3
POTE ankyrin domain family member B3

1

4

High-throughput

0.407

High

1336749

C170L
Cep170-like protein

1

3

High-throughput

0.407

High

1336756

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

20

High-throughput

0.407

High

1336745

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

0

High-throughput

0.316

High

1331438

VA0D2
V-type proton ATPase subunit d 2

1

0

High-throughput

0.282

High

169196

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

1218111

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

1336747

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1336760

TM14B
Transmembrane protein 14B

1

0

High-throughput

0.279

Low

1336762

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025