HitPredict

Interactor 1: MK13 (O15264)
Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)
Gene: MAPK13

Interactor 2: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32707033, 19135240
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 545
+	Hs
		625228 CDK2_HUMAN (22-320): 5.41e-146: 416: 37.26		TCPG_HUMAN (1-545): 0: 640: 100.00
+	Rn
		600467 MK03_RAT (15-354): 1.42e-143: 413: 43.23		TCPG_RAT (1-545): 0: 639: 97.80
+	Hs
		173858 MK13_HUMAN (1-365): 1.21e-159: 453: 100.00		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Sc
		691051 HOG1_YEAST (3-357): 3.03e-147: 424: 44.10		TCPG_YEAST (3-530): 0: 575: 58.88
+	Hs
		625579 CDK2_HUMAN (22-320): 5.41e-146: 416: 37.26		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		625220 CDK2_HUMAN (22-320): 5.41e-146: 416: 37.26		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Rn
		600455 MK03_RAT (15-354): 1.42e-143: 413: 43.23		TCPE_RAT (4-530): 0: 556: 32.14
+	Sc
		691072 HOG1_YEAST (3-357): 3.03e-147: 424: 44.10		TCPH_YEAST (5-543): 0: 544: 30.29
+	Hs
		800722 MK08_HUMAN (5-349): 1.76e-109: 328: 46.81		TCPG_HUMAN (1-545): 0: 640: 100.00
+	Hs
		573132 CDK2_HUMAN (22-320): 5.41e-146: 416: 37.26		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Rn
		600336 MK03_RAT (15-354): 1.42e-143: 413: 43.23		TCPA_RAT (10-536): 0: 545: 33.27
+	Hs
		864873 MK10_HUMAN (9-348): 8.79e-109: 327: 47.61		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		573163 MK08_HUMAN (5-349): 1.76e-109: 328: 46.81		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		173864 MK13_HUMAN (1-365): 1.21e-159: 453: 100.00		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Hs
		625246 CDK2_HUMAN (22-320): 5.41e-146: 416: 37.26		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Rn
		600476 MK03_RAT (15-354): 1.42e-143: 413: 43.23		TCPD_RAT (16-524): 3.05e-90: 288: 34.18
+	Hs
		800728 MK08_HUMAN (5-349): 1.76e-109: 328: 46.81		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56