Interactor 1: PPM1D (O15297)
Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1)
Gene: PPM1D

Interactor 2: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 16311512, 28027003
Identification Methods pull down, affinity chromatography technology, enzymatic study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PP2C~Pkinase
Common GO terms GO:0000086 - G2/M transition of mitotic cell cycle
GO:0004674 - protein serine/threonine kinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0046872 - metal ion binding
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 605
Hs

1 543
+ Hs
+ Hs
+ At
+ At
+ Hs
+ Sc
+ At
+ At
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024