Protein: SEM6A
Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1)

Gene: SEM6A, SEMA6A
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q9H2E6

Gene Ontology (top 5):
GO:0001755 - neural crest cell migration
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0007010 - cytoskeleton organization
GO:0007166 - cell surface receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1431739

ST14
Suppressor of tumorigenicity 14 protein

1

4

High-throughput

0.691

High

1116300

PTC1
Protein patched homolog 1

3

8

High-throughput

0.667

High

1431736

ITM2B
Integral membrane protein 2B

3

1

High-throughput

0.667

High

1431737

PCDG5
Protocadherin gamma-A5

2

3

High-throughput

0.628

High

1101420

SG2A2
Mammaglobin-A

1

2

High-throughput

0.618

High

222202

NCK2
Cytoplasmic protein NCK2

3

7

High-throughput

0.609

High

1350759

SG1C1
Secretoglobin family 1C member 1

1

0

High-throughput

0.578

High

380353

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

10

High-throughput

0.536

High

594100

NCK1
SH2/SH3 adapter protein NCK1

1

7

High-throughput

0.536

High

688626

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

11

High-throughput

0.536

High

1180961

HFE
Hereditary hemochromatosis protein

1

3

High-throughput

0.536

High

1431735

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

1

High-throughput

0.536

High

1239936

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.515

High

1431730

TMPS4
Transmembrane protease serine 4

1

4

High-throughput

0.515

High

467605

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.513

High

1393202

TM169
Transmembrane protein 169

1

0

High-throughput

0.513

High

320264

SRBS2
Sorbin and SH3 domain-containing protein 2

1

8

Small-scale

0.508

High

1416513

SRBS1
Sorbin and SH3 domain-containing protein 1

1

7

Small-scale

0.508

High

1431731

ITSN2
Intersectin-2

1

4

Small-scale

0.508

High

942399

EP3B
Epididymal secretory protein E3-beta

1

1

High-throughput

0.489

High

1177881

CL12B
C-type lectin domain family 12 member B

1

9

High-throughput

0.489

High

1286618

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

1

1

High-throughput

0.489

High

1359240

CA054
Uncharacterized protein C1orf54

1

5

High-throughput

0.489

High

1416824

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

6

High-throughput

0.489

High

1431729

CST9L
Cystatin-9-like

1

4

High-throughput

0.489

High

1431734

FBX2
F-box only protein 2

1

9

High-throughput

0.489

High

189832

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

374187

RASN
GTPase NRas

1

11

High-throughput

0.479

High

375937

RASK
GTPase KRas

1

11

High-throughput

0.479

High

601438

RHOQ
Rho-related GTP-binding protein RhoQ

1

5

High-throughput

0.479

High

710483

EPHA2
Ephrin type-A receptor 2

1

6

High-throughput

0.479

High

1087277

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

1151868

RHOH
Rho-related GTP-binding protein RhoH

1

6

High-throughput

0.479

High

1286901

TM11B
Transmembrane protease serine 11B

1

4

High-throughput

0.479

High

1404200

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

1431727

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

1280045

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

4

Small-scale

0.464

High

646939

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.458

High

693087

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

1031540

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.458

High

1041277

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1431728

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1431732

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1431733

EVL
Ena/VASP-like protein

1

0

Small-scale

0.458

High

1153904

SMAD2
Mothers against decapentaplegic homolog 2

1

1

High-throughput

0.437

High

1293143

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1381959

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1431241

DJC25
DnaJ homolog subfamily C member 25

1

8

High-throughput

0.437

High

1198756

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.328

High

1431738

INSL5
Insulin-like peptide INSL5

2

0

High-throughput

0.328

High

416648

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.279

Low

465860

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.279

Low

1310397

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

993742

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.261

Low


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Last updated: 11Aug2025