HitPredict

Interactor 1: RPC7 (O15318)
DNA-directed RNA polymerase III subunit RPC7 (RNA polymerase III subunit C7) (DNA-directed RNA polymerase III subunit G) (RNA polymerase III 32 kDa apha subunit) (RPC32-alpha) (RNA polymerase III 32 kDa subunit) (RPC32)
Gene: POLR3G

Interactor 2: RPC6 (Q9H1D9)
DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39)
Gene: POLR3F

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 35271311, 20154270, 19631370
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_3_Rpc31~RNA_pol_Rpc34
Common GO terms GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol
GO:0006359 - regulation of transcription by RNA polymerase III
and 5 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 223
Hs

1 316
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024