HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26748699
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 667 Hs			1 451
+	Hs
		175725 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		TBA8_HUMAN (1-440): 0: 701: 90.68
+	Hs
		175631 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		175671 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		933388 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		428490 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		934017 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		1175159 TRIM9_HUMAN (1-659): 6.49e-114: 359: 23.84		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		933810 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		933631 TRI36_HUMAN (1-647): 2.78e-95: 311: 24.59		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		1171443 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		1175202 TRI36_HUMAN (1-647): 2.78e-95: 311: 24.59		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		933491 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		933246 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		1170530 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		1172004 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA8_HUMAN (1-440): 0: 701: 90.68
+	Hs
		1161205 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBA3E_HUMAN (1-440): 0: 700: 96.59
+	Hs
		428268 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		933861 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		1282058 TRI63_HUMAN (1-380): 2.91e-86: 276: 24.09		TBA8_HUMAN (1-440): 0: 701: 90.68
+	Hs
		1317527 TRI55_HUMAN (1-378): 3.73e-80: 266: 23.44		TBA8_HUMAN (1-440): 0: 701: 90.68