HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	15805470
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 307
+	Hs
		177250 HDAC3_HUMAN (1-428): 0: 600: 100.00		PP1A_HUMAN (2-304): 0: 517: 43.89
+	Mm
		140248 HDAC1_MOUSE (3-385): 0: 588: 62.92		PP1A_MOUSE (2-304): 0: 518: 44.20
+	Hs
		737789 HDAC1_HUMAN (3-385): 0: 588: 62.92		PP1G_HUMAN (1-304): 0: 518: 43.81
+	Hs
		905880 HDAC1_HUMAN (3-385): 0: 588: 62.92		PP1A_HUMAN (2-304): 0: 517: 43.89
+	Hs
		737952 HDAC2_HUMAN (3-422): 0: 580: 58.63		PP1G_HUMAN (1-304): 0: 518: 43.81
+	Sp
		140582 PHD1_SCHPO (3-407): 0: 519: 56.27		PP2A2_SCHPO (2-307): 0: 507: 63.40
+	Hs
		738016 HDAC8_HUMAN (6-367): 8.28e-143: 414: 41.71		PP1G_HUMAN (1-304): 0: 518: 43.81
+	Hs
		738102 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		PP1G_HUMAN (1-304): 0: 518: 43.81
+	Hs
		906183 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		PP1A_HUMAN (2-304): 0: 517: 43.89