HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: ANR12 (Q6UB98)
Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein)
Gene: ANKRD12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	18377363, 23752268
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 2062
+	Hs
		177326 HDAC3_HUMAN (1-428): 0: 600: 100.00		ANR11_HUMAN (1-1346): 4.28e-56: 218: 21.96
+	Hs
		166921 HDAC1_HUMAN (3-385): 0: 588: 62.92		ANR28_HUMAN (28-272): 3.62e-49: 194: 14.39
+	Hs
		1219802 HDAC2_HUMAN (3-422): 0: 580: 58.63		ANKH1_HUMAN (110-761): 4.12e-44: 179: 11.60
+	Hs
		257609 HDAC1_HUMAN (3-385): 0: 588: 62.92		ANR17_HUMAN (145-882): 3.19e-40: 166: 11.23
+	Hs
		257678 HDAC2_HUMAN (3-422): 0: 580: 58.63		ANR17_HUMAN (145-882): 3.19e-40: 166: 11.23
+	Hs
		1038762 HDAC1_HUMAN (3-385): 0: 588: 62.92		RAI14_HUMAN (85-960): 1.59e-24: 114: 10.77
+	Hs
		1164384 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		POTEE_HUMAN (78-773): 6.08e-76: 278: 18.26
+	Hs
		60435 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		POTEF_HUMAN (78-794): 3.03e-75: 276: 17.74
+	Hs
		1318059 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		UACA_HUMAN (317-1035): 9.1e-09: 63.1: 13.06