HitPredict

Interactor 1: BIRC5 (O15392)
Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)
Gene: BIRC5

Interactor 2: UBP19 (O94966)
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)
Gene: USP19

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35918893
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 1318
+	Hs
		301385 BIRC3_HUMAN (3-96): 8.83e-22: 91.7: 27.66		UBP19_HUMAN (1-1318): 0: 1245: 100.00
+	Hs
		301386 BIRC2_HUMAN (10-88): 1.01e-18: 82.9: 27.85		UBP19_HUMAN (1-1318): 0: 1245: 100.00
+	Hs
		301374 XIAP_HUMAN (11-87): 7.51e-14: 69: 28.57		UBP19_HUMAN (1-1318): 0: 1245: 100.00
+	Hs
		1036241 BIRC3_HUMAN (3-96): 8.83e-22: 91.7: 27.66		UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42
+	Hs
		1036377 BIRC2_HUMAN (10-88): 1.01e-18: 82.9: 27.85		UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42
+	Mm
		1141990 XIAP_MOUSE (11-87): 5.95e-14: 69.4: 27.27		UBP15_MOUSE (485-1219): 1.25e-154: 493: 33.42
+	Hs
		849996 XIAP_HUMAN (11-87): 7.51e-14: 69: 28.57		UBP11_HUMAN (459-1228): 1.44e-151: 484: 30.84
+	Hs
		177733 BIRC5_HUMAN (1-142): 2.27e-60: 184: 100.00		UBP22_HUMAN (458-838): 9.18e-65: 231: 19.02
+	Hs
		777082 BIRC6_HUMAN (8-88): 8.14e-36: 132: 37.04		UBP8_HUMAN (781-1222): 3.94e-67: 250: 19.39
+	Hs
		271165 BIRC7_HUMAN (7-104): 1.33e-33: 121: 29.59		UBP2_HUMAN (796-1219): 6.05e-73: 257: 20.54
+	Hs
		177729 BIRC5_HUMAN (1-142): 2.27e-60: 184: 100.00		UBP35_HUMAN (1046-1284): 2.03e-43: 174: 26.42
+	Hs
		1035953 BIRC3_HUMAN (3-96): 8.83e-22: 91.7: 27.66		UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64
+	Hs
		1036312 BIRC2_HUMAN (10-88): 1.01e-18: 82.9: 27.85		UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64
+	Hs
		957751 XIAP_HUMAN (11-87): 7.51e-14: 69: 28.57		UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64
+	Hs
		1036163 BIRC3_HUMAN (3-96): 8.83e-22: 91.7: 27.66		UBP35_HUMAN (1046-1284): 2.03e-43: 174: 26.42