HitPredict

Interactor 1: IPO8 (O15397)
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)
Gene: IPO8

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 465
+	Hs
		312165 IPO7_HUMAN (1-1031): 0: 819: 64.57		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		226978 XPO2_HUMAN (2-1000): 4.14e-168: 520: 18.06		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228265 TNPO1_HUMAN (12-883): 1.02e-146: 462: 12.75		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227476 IMB1_HUMAN (5-859): 6.55e-113: 371: 12.47		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	At
		97109 F4J737_ARATH (1-1014): 0: 638: 26.34		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		96637 SAD2_ARATH (1-1010): 0: 637: 28.65		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		1092451 XPO2_ARATH (13-995): 3.11e-143: 455: 15.32		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		1091763 TNPO1_ARATH (3-858): 2.39e-118: 386: 13.13		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		1092036 IMB1_ARATH (1-819): 3.55e-118: 386: 13.40		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	Hs
		475772 IMB1_HUMAN (5-859): 6.55e-113: 371: 12.47		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47