HitPredict

Interactor 1: IPO8 (O15397)
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)
Gene: IPO8

Interactor 2: PE2R3 (P43115)
Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)
Gene: PTGER3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 390
+	Hs
		178120 IPO8_HUMAN (1-1037): 0: 846: 100.00		APJ_HUMAN (37-390): 1.01e-63: 210: 14.41
+	Hs
		312201 IPO7_HUMAN (1-1031): 0: 819: 64.57		PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00
+	Hs
		825675 XPO2_HUMAN (2-1000): 4.14e-168: 520: 18.06		MTR1B_HUMAN (17-378): 3.14e-55: 187: 19.84
+	Hs
		623000 Q4LE60_HUMAN (12-883): 2.89e-144: 460: 12.10		EDNRB_HUMAN (5-388): 2.31e-59: 200: 13.85
+	Hs
		155546 TNPO2_HUMAN (12-883): 9.66e-136: 433: 12.21		PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00
+	Hs
		155531 TNPO2_HUMAN (12-883): 9.66e-136: 433: 12.21		EDNRB_HUMAN (5-388): 2.31e-59: 200: 13.85
+	Hs
		793166 IPO11_HUMAN (1-996): 3.31e-122: 399: 16.09		PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00
+	Hs
		793145 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00
+	Hs
		723430 IPO11_HUMAN (1-996): 3.31e-122: 399: 16.09		APJ_HUMAN (37-390): 1.01e-63: 210: 14.41
+	Hs
		723119 IPO11_HUMAN (1-996): 3.31e-122: 399: 16.09		OPRM_HUMAN (3-389): 2.49e-61: 204: 17.13
+	Hs
		623016 IPO11_HUMAN (1-996): 3.31e-122: 399: 16.09		EDNRB_HUMAN (5-388): 2.31e-59: 200: 13.85
+	Hs
		686814 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		GP183_HUMAN (24-387): 3.73e-60: 200: 15.57
+	Hs
		429042 IMB1_HUMAN (5-859): 6.55e-113: 371: 12.47		ADRB2_HUMAN (15-367): 1.23e-67: 221: 13.37
+	Hs
		825730 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		MTR1B_HUMAN (17-378): 3.14e-55: 187: 19.84