Interactor 1: ARC1B (O15143)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARPC1B

Interactor 2: ARPC2 (O15144)
Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)
Gene: ARPC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.763

The method score is based on:

Property Details
Experiments 35271311, 28524877, 38334954, 39422127, 20603326, 26186194, 28514442, 29568061, 24981860, 33961781, 34349018, 31839598, 26655834, 20404198, unassigned3799
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003779 - actin binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 372
Hs

1 300
+ Dm
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025