Protein: ARPC1
Actin-related protein 2/3 complex subunit 1 (Arp2/3 complex 41 kDa subunit) (p41-ARC)

Gene: ARPC1, ARC40
Organism: Saccharomyces cerevisiae S288C
Interactions: 95
UniProt ID: P38328

Gene Ontology (top 5):
GO:0005885 - Arp2/3 protein complex
GO:0015629 - actin cytoskeleton
GO:0030479 - actin cortical patch
GO:0034314 - Arp2/3 complex-mediated actin nucleation
GO:0043130 - ubiquitin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

736090

ARP2
Actin-related protein 2

14

18

Small-scale

0.984

High

798153

ARP3
Actin-related protein 3

8

18

Small-scale

0.973

High

750331

ARPC4
Actin-related protein 2/3 complex subunit 4

7

5

Small-scale

0.968

High

798146

ARPC5
Actin-related protein 2/3 complex subunit 5

5

5

Small-scale

0.925

High

798156

ARPC2
Actin-related protein 2/3 complex subunit 2

8

4

Small-scale

0.752

High

798166

ARPC3
Actin-related protein 2/3 complex subunit 3

7

5

Small-scale

0.750

High

798174

LAS17
Proline-rich protein LAS17

7

11

Small-scale

0.744

High

798163

MYO5
Myosin-5

5

16

Small-scale

0.715

High

798167

CORO
Coronin-like protein

1

16

High-throughput

0.665

High

744839

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

3

10

Small-scale

0.658

High

778978

MYO3
Myosin-3

2

20

Small-scale

0.639

High

751849

SLA2
Protein SLA2

2

16

High-throughput

0.614

High

790573

VRP1
Verprolin

2

15

High-throughput

0.614

High

798171

AIM7
Protein AIM7

2

5

Small-scale

0.605

High

798140

LIS1
Nuclear distribution protein PAC1

1

19

High-throughput

0.595

High

739068

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

2

9

Small-scale

0.595

High

562957

CAPZB
F-actin-capping protein subunit beta

1

8

High-throughput

0.541

High

605310

CAP
Adenylyl cyclase-associated protein

1

1

High-throughput

0.541

High

672305

RV161
Reduced viability upon starvation protein 161

1

2

High-throughput

0.541

High

743333

FIMB
Fimbrin

1

6

High-throughput

0.541

High

798139

RV167
Reduced viability upon starvation protein 167

1

14

High-throughput

0.541

High

798145

PRK1
Actin-regulating kinase PRK1

1

8

High-throughput

0.541

High

798151

BBC1
Myosin tail region-interacting protein MTI1

1

16

High-throughput

0.541

High

798154

INP52
Polyphosphatidylinositol phosphatase INP52

1

2

High-throughput

0.541

High

798159

ARK1
Actin-regulating kinase 1

1

8

High-throughput

0.541

High

743978

RAD23
UV excision repair protein RAD23

1

7

High-throughput

0.515

High

798152

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.514

High

526551

HSP72
Heat shock protein SSA2

2

18

High-throughput

0.504

High

544683

SSB1
Ribosome-associated molecular chaperone SSB1

2

19

High-throughput

0.504

High

798149

BNI1
Protein BNI1

1

4

High-throughput

0.501

High

728703

ACBP
Acyl-CoA-binding protein

1

1

High-throughput

0.494

High

751575

SNC2
Synaptobrevin homolog 2

1

1

High-throughput

0.494

High

798161

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

13

High-throughput

0.494

High

798172

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

2

High-throughput

0.494

High

738374

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

4

High-throughput

0.489

High

791048

NOP4
Nucleolar protein 4

1

12

High-throughput

0.489

High

798135

SSZ1
Ribosome-associated complex subunit SSZ1

1

12

High-throughput

0.489

High

798158

YNE0
Putative alanyl-tRNA editing protein alaX

1

6

High-throughput

0.489

High

798164

POB3
FACT complex subunit POB3

1

7

High-throughput

0.489

High

587304

ABP1
Actin-binding protein

1

12

High-throughput

0.479

High

644766

CLH
Clathrin heavy chain

1

8

High-throughput

0.479

High

798136

END3
Actin cytoskeleton-regulatory complex protein END3

1

8

High-throughput

0.479

High

798147

GTS1
Protein GTS1

1

2

High-throughput

0.479

High

798176

ENT1
Epsin-1

1

2

High-throughput

0.479

High

509520

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

14

Small-scale

0.457

High

359469

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

7

High-throughput

0.457

High

367744

ENO1
Enolase 1

1

4

High-throughput

0.457

High

403494

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

8

High-throughput

0.457

High

408572

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

1

High-throughput

0.457

High

439322

PDC1
Pyruvate decarboxylase isozyme 1

1

2

High-throughput

0.457

High

572569

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.457

High

645398

XRN1
5'-3' exoribonuclease 1

1

3

High-throughput

0.457

High

361433

SODC
Superoxide dismutase [Cu-Zn]

1

2

High-throughput

0.437

High

392648

HSP82
ATP-dependent molecular chaperone HSP82

1

16

High-throughput

0.437

High

430838

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

6

Small-scale

0.437

High

556567

STE6
Alpha-factor-transporting ATPase

1

1

High-throughput

0.437

High

571031

CHS2
Chitin synthase 2

1

1

High-throughput

0.437

High

579299

HSC82
ATP-dependent molecular chaperone HSC82

1

16

High-throughput

0.437

High

621361

METK2
S-adenosylmethionine synthase 2

1

2

High-throughput

0.437

High

672492

SYNM
Asparagine--tRNA ligase, mitochondrial

1

7

High-throughput

0.437

High

677875

ADY2
Accumulation of dyads protein 2

1

1

High-throughput

0.437

High

706949

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

712783

CHS3
Chitin synthase 3

1

1

High-throughput

0.437

High

724263

SNC1
Synaptobrevin homolog 1

1

4

High-throughput

0.437

High

747693

ATO2
Ammonia transport outward protein 2

1

1

High-throughput

0.437

High

757568

YOX1
Homeobox protein YOX1

1

6

High-throughput

0.437

High

798137

LAA1
AP-1 accessory protein LAA1

1

4

High-throughput

0.437

High

798148

FKS2
1,3-beta-glucan synthase component GSC2

1

1

High-throughput

0.437

High

798150

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

11

High-throughput

0.437

High

798155

TNA1
High-affinity nicotinic acid transporter

1

2

High-throughput

0.437

High

798162

GIS1
Transcriptional activator/repressor GIS1

1

4

High-throughput

0.437

High

798165

ENT2
Epsin-2

1

3

High-throughput

0.437

High

798169

MED7
Mediator of RNA polymerase II transcription subunit 7

1

1

Small-scale

0.437

High

798170

GRE2
NADPH-dependent methylglyoxal reductase GRE2

1

2

High-throughput

0.437

High

798175

AHA1
Hsp90 co-chaperone AHA1

1

3

High-throughput

0.417

High

427252

RLA0
Large ribosomal subunit protein uL10

1

9

High-throughput

0.407

High

510442

HSP77
Import motor subunit, mitochondrial

1

16

High-throughput

0.407

High

523780

HSP71
Heat shock protein SSA1

1

18

High-throughput

0.407

High

655445

RS3A2
Small ribosomal subunit protein eS1B

1

5

High-throughput

0.407

High

670636

SIS1
Protein SIS1

1

14

High-throughput

0.407

High

675960

MAS5
Mitochondrial protein import protein MAS5

1

13

High-throughput

0.407

High

752197

HSP78
Heat shock protein 78, mitochondrial

1

6

High-throughput

0.407

High

798141

SSB2
Ribosome-associated molecular chaperone SSB2

1

19

High-throughput

0.407

High

798144

JEM1
DnaJ-like chaperone JEM1

1

11

High-throughput

0.407

High

798157

PFD4
Prefoldin subunit 4

1

4

High-throughput

0.407

High

740399

MED17
Mediator of RNA polymerase II transcription subunit 17

2

0

Small-scale

0.300

High

367486

TRPE
Anthranilate synthase component 1

1

0

High-throughput

0.282

High

455615

TRPD
Anthranilate phosphoribosyltransferase

1

0

High-throughput

0.282

High

788415

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.282

High

798168

CSC1
Calcium permeable stress-gated cation channel 1

1

0

High-throughput

0.279

Low

798138

FLC2
Flavin carrier protein 2

1

0

High-throughput

0.249

Low

798142

FDO1
Protein FDO1

1

0

High-throughput

0.249

Low

798143

KHA1

1

0

High-throughput

0.249

Low

798160

DIA1
Protein DIA1

1

0

High-throughput

0.249

Low

798173

PST1
Cell wall mannoprotein PST1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025