HitPredict - High confidence protein-protein interactions

Interactor 1: COPT1 (O15431)
High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1) [Cleaved into: Truncated CTR1 form]
Gene: SLC31A1

Interactor 2: COPT1 (O15431)
High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1) [Cleaved into: Truncated CTR1 form]
Gene: SLC31A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	12466020, 16501047, 19240214
Identification Methods	two hybrid, molecular sieving, cross-linking study, 3D electron microscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005375 - copper ion transmembrane transporter activity GO:0005507 - copper ion binding GO:0005886 - plasma membrane GO:0006825 - copper ion transport and 16 others more... GO:0006878 - intracellular copper ion homeostasis GO:0014704 - intercalated disc GO:0015080 - silver ion transmembrane transporter activity GO:0015677 - copper ion import GO:0015679 - plasma membrane copper ion transport GO:0016323 - basolateral plasma membrane GO:0016324 - apical plasma membrane GO:0031901 - early endosome membrane GO:0031902 - late endosome membrane GO:0036324 - vascular endothelial growth factor receptor-2 signaling pathway GO:0042908 - xenobiotic transport GO:0042910 - xenobiotic transmembrane transporter activity GO:0051259 - protein complex oligomerization GO:0051649 - establishment of localization in cell GO:0055038 - recycling endosome membrane GO:1902601 - silver ion transmembrane transport
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	190
Hs

1	190

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Last updated: 15 Jul 2024