HitPredict

Interactor 1: CCL16 (O15467)
C-C motif chemokine 16 (Chemokine CC-4) (HCC-4) (Chemokine LEC) (IL-10-inducible chemokine) (LCC-1) (Liver-expressed chemokine) (Lymphocyte and monocyte chemoattractant) (LMC) (Monotactin-1) (MTN-1) (NCC-4) (Small-inducible cytokine A16)
Gene: CCL16

Interactor 2: CXCR5 (P32302)
C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185)
Gene: CXCR5

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11470772
Identification Methods	biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 120 Hs			1 372
+	Hs
		526561 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		CXCR5_HUMAN (1-372): 1.08e-91: 281: 100.00
+	Hs
		180160 CCL16_HUMAN (1-120): 3.49e-39: 129: 100.00		CCR2_HUMAN (30-349): 1.29e-72: 232: 29.69
+	Hs
		180158 CCL16_HUMAN (1-120): 3.49e-39: 129: 100.00		CCR1_HUMAN (33-367): 2.52e-71: 228: 27.68
+	Hs
		830629 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		CXCR3_HUMAN (14-350): 4.44e-75: 238: 39.76
+	Hs
		849619 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		CCR3_HUMAN (21-367): 2.57e-74: 236: 28.45
+	Hs
		561732 CL3L1_HUMAN (1-95): 2.37e-34: 115: 34.38		CCR3_HUMAN (21-367): 2.57e-74: 236: 28.45
+	Hs
		526564 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		CCR3_HUMAN (21-367): 2.57e-74: 236: 28.45
+	Hs
		783833 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		CCR2_HUMAN (30-349): 1.29e-72: 232: 29.69
+	Mm
		500591 CCL3_MOUSE (1-95): 9.34e-34: 114: 37.50		CCR3_MOUSE (29-367): 5.51e-73: 232: 27.35
+	Hs
		180161 CCL16_HUMAN (1-120): 3.49e-39: 129: 100.00		CCR5_HUMAN (23-368): 2.9e-66: 215: 26.59
+	Hs
		561728 CL3L1_HUMAN (1-95): 2.37e-34: 115: 34.38		CCR1_HUMAN (33-367): 2.52e-71: 228: 27.68
+	Hs
		526560 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		CCR1_HUMAN (33-367): 2.52e-71: 228: 27.68
+	Hs
		849654 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		CCR5_HUMAN (23-368): 2.9e-66: 215: 26.59
+	Hs
		1305163 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		ACKR4_HUMAN (7-349): 3.48e-65: 212: 27.99
+	Hs
		561733 CL3L1_HUMAN (1-95): 2.37e-34: 115: 34.38		CCR5_HUMAN (23-368): 2.9e-66: 215: 26.59
+	Hs
		526565 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		CCR5_HUMAN (23-368): 2.9e-66: 215: 26.59
+	Mm
		500590 CCL3_MOUSE (1-95): 9.34e-34: 114: 37.50		CCR1_MOUSE (22-367): 7.54e-65: 211: 28.82
+	Hs
		180162 CCL16_HUMAN (1-120): 3.49e-39: 129: 100.00		CCR8_HUMAN (42-339): 4.85e-44: 157: 31.21
+	Hs
		134400 CCL13_HUMAN (1-99): 3.28e-35: 118: 31.00		ACKR2_HUMAN (46-340): 4.16e-36: 137: 32.23
+	Hs
		134356 CCL4_HUMAN (1-94): 7.42e-34: 114: 38.95		ACKR2_HUMAN (46-340): 4.16e-36: 137: 32.23