Protein: UBXN1
UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein)

Gene: UBXN1
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q04323

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

874846

TERA
Transitional endoplasmic reticulum ATPase

8

16

Small-scale

0.974

High

475650

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

10

20

Small-scale

0.973

High

979370

UBQL2
Ubiquilin-2

3

15

High-throughput

0.843

High

227228

PRKN
E3 ubiquitin-protein ligase parkin

3

14

Small-scale

0.839

High

872145

RD23A
UV excision repair protein RAD23 homolog A

2

20

High-throughput

0.783

High

509640

UBL4A
Ubiquitin-like protein 4A

2

20

Small-scale

0.754

High

803499

BAG6
Large proline-rich protein BAG6

2

15

Small-scale

0.754

High

979375

UBQL1
Ubiquilin-1

1

15

High-throughput

0.740

High

408607

KPCB
Protein kinase C beta type

2

1

High-throughput

0.737

High

979286

UBXN1
UBX domain-containing protein 1

1

9

High-throughput

0.698

High

979378

PLAP
Phospholipase A-2-activating protein

4

6

High-throughput

0.697

High

979297

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

4

9

High-throughput

0.694

High

979344

BTBD9
BTB/POZ domain-containing protein 9

4

9

High-throughput

0.694

High

979356

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

4

9

High-throughput

0.694

High

979321

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

8

High-throughput

0.691

High

979353

UBXN6
UBX domain-containing protein 6

1

6

High-throughput

0.691

High

572930

PRS6A
26S proteasome regulatory subunit 6A

3

14

High-throughput

0.667

High

979342

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

3

2

High-throughput

0.667

High

979355

BTBD1
BTB/POZ domain-containing protein 1

3

11

High-throughput

0.667

High

979372

TRIM1
Probable E3 ubiquitin-protein ligase MID2

3

20

High-throughput

0.667

High

515406

CDK4
Cyclin-dependent kinase 4

1

1

High-throughput

0.665

High

979318

Q7KZS0
SUMO-conjugating enzyme UBC9

1

6

High-throughput

0.665

High

979293

CUL1
Cullin-1

3

12

Small-scale

0.656

High

979359

MARH7
E3 ubiquitin-protein ligase MARCHF7

3

0

High-throughput

0.638

High

979294

CUL2
Cullin-2

2

12

High-throughput

0.628

High

930159

UBC9
SUMO-conjugating enzyme UBC9

1

7

High-throughput

0.621

High

299357

UBXN7
UBX domain-containing protein 7

1

10

High-throughput

0.618

High

397924

ISG15
Ubiquitin-like protein ISG15

1

20

Small-scale

0.618

High

979336

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

1

High-throughput

0.618

High

979339

FAF2
FAS-associated factor 2

1

10

High-throughput

0.618

High

979345

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.618

High

979352

ASPC1
Tether containing UBX domain for GLUT4

1

6

High-throughput

0.618

High

979376

FAF1
FAS-associated factor 1

1

13

High-throughput

0.618

High

979377

NSF1C
NSFL1 cofactor p47

1

5

Small-scale

0.618

High

979333

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

7

Small-scale

0.611

High

979364

RNF12
E3 ubiquitin-protein ligase RLIM

2

8

High-throughput

0.611

High

979380

TCAF1
TRPM8 channel-associated factor 1

3

1

High-throughput

0.609

High

979325

YAF2
YY1-associated factor 2

2

0

High-throughput

0.602

High

979347

AASD1
Alanyl-tRNA editing protein Aarsd1

2

0

High-throughput

0.602

High

979334

TITIN
Titin

1

0

High-throughput

0.586

High

979290

BIRC3
Baculoviral IAP repeat-containing protein 3

2

5

Small-scale

0.584

High

979319

GET4
Golgi to ER traffic protein 4 homolog

2

2

Small-scale

0.584

High

979340

OPTN
Optineurin

2

5

High-throughput

0.584

High

117390

BACH
Cytosolic acyl coenzyme A thioester hydrolase

2

0

High-throughput

0.580

High

979348

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

0

High-throughput

0.580

High

979382

EMIL1
EMILIN-1

2

2

High-throughput

0.574

High

979360

TRI39
E3 ubiquitin-protein ligase TRIM39

1

7

High-throughput

0.573

High

979291

BIRC2
Baculoviral IAP repeat-containing protein 2

2

5

Small-scale

0.571

High

749403

BRCA1
Breast cancer type 1 susceptibility protein

1

8

Small-scale

0.561

High

979346

BARD1
BRCA1-associated RING domain protein 1

1

1

Small-scale

0.561

High

979330

SHKB1
SH3KBP1-binding protein 1

2

10

High-throughput

0.558

High

196296

PJA2
E3 ubiquitin-protein ligase Praja-2

1

6

High-throughput

0.536

High

304131

UBR5
E3 ubiquitin-protein ligase UBR5

1

12

High-throughput

0.536

High

305170

UBE4B
Ubiquitin conjugation factor E4 B

1

3

High-throughput

0.536

High

591312

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

7

High-throughput

0.536

High

979287

UBE3A
Ubiquitin-protein ligase E3A

1

10

High-throughput

0.536

High

979295

CUL3
Cullin-3

1

12

High-throughput

0.536

High

979304

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.536

High

979308

KLH12
Kelch-like protein 12

1

3

High-throughput

0.536

High

979309

KLH22
Kelch-like protein 22

1

6

High-throughput

0.536

High

979311

UBR4
E3 ubiquitin-protein ligase UBR4

1

5

High-throughput

0.536

High

979313

C102B
Coiled-coil domain-containing protein 102B

1

3

High-throughput

0.536

High

979316

KLH10
Kelch-like protein 10

1

3

High-throughput

0.536

High

979322

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

979323

UBR1
E3 ubiquitin-protein ligase UBR1

1

5

High-throughput

0.536

High

979324

UBR2
E3 ubiquitin-protein ligase UBR2

1

5

High-throughput

0.536

High

979326

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.536

High

979329

NPL4
Nuclear protein localization protein 4 homolog

1

6

High-throughput

0.536

High

979335

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

6

High-throughput

0.536

High

979338

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

979341

VCIP1
Deubiquitinating protein VCPIP1

1

3

High-throughput

0.536

High

979350

BTBD2
BTB/POZ domain-containing protein 2

1

8

High-throughput

0.536

High

979373

AMFR
E3 ubiquitin-protein ligase AMFR

1

10

High-throughput

0.536

High

979362

HOME2
Homer protein homolog 2

1

0

Small-scale

0.529

High

979328

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

3

High-throughput

0.515

High

979366

BABA1
BRISC and BRCA1-A complex member 1

1

1

High-throughput

0.515

High

359872

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

11

High-throughput

0.515

High

979298

DCTN1
Dynactin subunit 1

1

4

High-throughput

0.515

High

979368

HSPB7
Heat shock protein beta-7

1

1

High-throughput

0.515

High

979379

RNF11
RING finger protein 11

1

5

High-throughput

0.515

High

529009

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

868439

ATX1
Ataxin-1

1

0

High-throughput

0.513

High

979300

CD5R1
Cyclin-dependent kinase 5 activator 1

1

0

High-throughput

0.513

High

449689

HMGB1
High mobility group protein B1

1

3

Small-scale

0.508

High

812820

PA24A
Cytosolic phospholipase A2

1

2

Small-scale

0.508

High

979331

WDR20
WD repeat-containing protein 20

1

0

High-throughput

0.493

High

979363

ASF1B
Histone chaperone ASF1B

1

0

High-throughput

0.493

High

281606

WFS1
Wolframin

1

0

High-throughput

0.493

High

388390

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.493

High

742237

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

979288

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.493

High

59749

KLRG2
Killer cell lectin-like receptor subfamily G member 2

1

2

High-throughput

0.489

High

201088

AQP9
Aquaporin-9

1

2

High-throughput

0.489

High

380204

A1BG
Alpha-1B-glycoprotein

1

1

High-throughput

0.489

High

48338

ESYT2
Extended synaptotagmin-2

1

4

High-throughput

0.479

High

210898

GET3
ATPase GET3

1

1

Small-scale

0.479

High

213532

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

4

Small-scale

0.479

High

225868

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

3

High-throughput

0.479

High

244319

BRD4
Bromodomain-containing protein 4

1

6

High-throughput

0.479

High

294735

RECQ4
ATP-dependent DNA helicase Q4

1

4

High-throughput

0.479

High

346584

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

503939

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.479

High

515838

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

3

High-throughput

0.479

High

542289

PLAK
Junction plakoglobin

1

3

High-throughput

0.479

High

569625

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

617523

CRCM
Colorectal mutant cancer protein

1

3

High-throughput

0.479

High

632251

TNR6
Tumor necrosis factor receptor superfamily member 6

1

7

High-throughput

0.479

High

637392

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.479

High

675159

CLIP1
CAP-Gly domain-containing linker protein 1

1

3

High-throughput

0.479

High

830277

CASP4
Caspase-4

1

2

High-throughput

0.479

High

832389

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.479

High

874078

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

1

Small-scale

0.479

High

890622

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.479

High

921228

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

Small-scale

0.479

High

963593

E2F1
Transcription factor E2F1

1

2

High-throughput

0.479

High

970756

DSG1
Desmoglein-1

1

3

High-throughput

0.479

High

979292

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

979296

CUL4A
Cullin-4A

1

12

High-throughput

0.479

High

979299

SMC1A
Structural maintenance of chromosomes protein 1A

1

4

High-throughput

0.479

High

979301

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

1

High-throughput

0.479

High

979303

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

979306

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

High-throughput

0.479

High

979307

DUS6
Dual specificity protein phosphatase 6

1

3

High-throughput

0.479

High

979310

DCAF6
DDB1- and CUL4-associated factor 6

1

2

High-throughput

0.479

High

979312

CP135
Centrosomal protein of 135 kDa

1

3

High-throughput

0.479

High

979317

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.479

High

979349

RN126
E3 ubiquitin-protein ligase RNF126

1

7

Small-scale

0.479

High

979351

HDAC8
Histone deacetylase 8

1

3

High-throughput

0.479

High

979357

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

979358

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

979361

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

Small-scale

0.479

High

979365

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

979369

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

979371

ATIF1
ATPase inhibitor, mitochondrial

1

1

High-throughput

0.479

High

979374

MYO6
Unconventional myosin-VI

1

4

High-throughput

0.479

High

979332

Q8WU02
C9orf61 protein

1

3

High-throughput

0.470

High

640094

MOES
Moesin

1

0

High-throughput

0.458

High

823913

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

906421

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

0

High-throughput

0.458

High

979305

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.458

High

979337

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

979354

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

Small-scale

0.458

High

979367

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.458

High

979381

MAGD1
Melanoma-associated antigen D1

1

0

High-throughput

0.458

High

496890

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

979315

PKHA7
Pleckstrin homology domain-containing family A member 7

1

12

High-throughput

0.445

High

979327

GMCL2
Germ cell-less protein-like 2

1

5

High-throughput

0.445

High

979302

EREP1
Endosomal transmembrane epsin interactor 1

1

5

High-throughput

0.439

High

398516

PPB1
Alkaline phosphatase, placental type

1

2

High-throughput

0.437

High

979289

DSC1
Desmocollin-1

1

2

High-throughput

0.437

High

979314

RNF43
E3 ubiquitin-protein ligase RNF43

1

13

High-throughput

0.437

High

979320

MAVS
Mitochondrial antiviral-signaling protein

1

4

Small-scale

0.437

High

979343

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

3

High-throughput

0.437

High

831246

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.408

High

319541

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

560054

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

231500

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

352077

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

887818

CD81
CD81 antigen

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024