HitPredict

Interactor 1: RPAC1 (O15160)
DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)
Gene: POLR1C

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	32296183, 24981860, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 172
+	Hs
		180444 RPAC1_HUMAN (1-346): 6.26e-179: 501: 100.00		RPC8_HUMAN (1-172): 5.31e-54: 171: 18.72
+	Sc
		459066 RPAC1_YEAST (10-338): 1.99e-143: 410: 44.88		RPC8_YEAST (1-158): 1.08e-49: 160: 19.39
+	Dm
		1482202 Q9VMX3_DROME (30-343): 7.46e-139: 399: 53.97		Q9VTL6_DROME (1-157): 2e-51: 166: 17.79
+	Hs
		621619 RPB3_HUMAN (45-346): 4.02e-105: 311: 26.38		RPB7_HUMAN (1-172): 1.49e-76: 227: 100.00
+	Sc
		594294 RPB3_YEAST (46-346): 5.67e-100: 299: 25.74		RPB7_YEAST (1-171): 4.47e-63: 193: 42.78
+	Hs
		621805 RPB3_HUMAN (45-346): 4.02e-105: 311: 26.38		RPC8_HUMAN (1-172): 5.31e-54: 171: 18.72
+	Sp
		154254 RPB3_SCHPO (50-344): 8.24e-89: 270: 24.50		RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42
+	Sc
		594305 RPB3_YEAST (46-346): 5.67e-100: 299: 25.74		RPC8_YEAST (1-158): 1.08e-49: 160: 19.39