HitPredict

Interactor 1: YKT6 (O15498)
Synaptobrevin homolog YKT6 (EC 2.3.1.-)
Gene: YKT6

Interactor 2: SNAA (P54920)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)
Gene: NAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNAP~Synaptobrevin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 295
+	Hs
		263203 SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60		SNAA_HUMAN (1-295): 2.13e-113: 330: 100.00
+	Dm
		1095592 Q9W3M8_DROME (1-196): 9.21e-71: 215: 61.74		SNAP_DROME (5-295): 7.84e-105: 308: 61.51
+	Hs
		850546 VAMP7_HUMAN (28-193): 7.9e-57: 180: 22.03		SNAA_HUMAN (1-295): 2.13e-113: 330: 100.00
+	Dm
		115802 M9PGI6_DROME (3-195): 3.74e-59: 185: 21.03		SNAP_DROME (5-295): 7.84e-105: 308: 61.51
+	Dm
		1095560 Q7JYX5_DROME (28-194): 7.94e-54: 172: 25.84		SNAP_DROME (5-295): 7.84e-105: 308: 61.51
+	Sc
		696563 YKT6_YEAST (1-198): 9.98e-69: 209: 47.00		SEC17_YEAST (8-294): 4.63e-88: 266: 34.48
+	Zm
		31296 A0A1D6KH00_MAIZE (21-194): 2.93e-57: 192: 18.18		A0A1D6PZ82_MAIZE (5-272): 3.97e-89: 271: 36.80
+	Hs
		180923 YKT6_HUMAN (1-198): 2.95e-72: 218: 100.00		SNAG_HUMAN (4-265): 6.75e-68: 215: 23.40
+	Sc
		605825 SEC22_YEAST (1-192): 2.06e-45: 151: 21.32		SEC17_YEAST (8-294): 4.63e-88: 266: 34.48
+	Hs
		263338 SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60		SNAG_HUMAN (4-265): 6.75e-68: 215: 23.40
+	Dm
		1353755 Q9W3M8_DROME (1-196): 9.21e-71: 215: 61.74		Q9U6R9_DROME (4-265): 3.84e-58: 190: 18.49
+	Hs
		850592 VAMP7_HUMAN (28-193): 7.9e-57: 180: 22.03		SNAG_HUMAN (4-265): 6.75e-68: 215: 23.40
+	Dm
		1366632 Q9W3M8_DROME (1-196): 9.21e-71: 215: 61.74		Q9VH25_DROME (18-265): 1.8e-53: 177: 17.53
+	Dm
		115822 M9PGI6_DROME (3-195): 3.74e-59: 185: 21.03		Q9U6R9_DROME (4-265): 3.84e-58: 190: 18.49
+	Dm
		115828 M9PGI6_DROME (3-195): 3.74e-59: 185: 21.03		Q9VH25_DROME (18-265): 1.8e-53: 177: 17.53
+	Dm
		1178116 Q7JYX5_DROME (28-194): 7.94e-54: 172: 25.84		Q9U6R9_DROME (4-265): 3.84e-58: 190: 18.49
+	Dm
		1178122 Q7JYX5_DROME (28-194): 7.94e-54: 172: 25.84		Q9VH25_DROME (18-265): 1.8e-53: 177: 17.53