HitPredict

Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	26871637
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019899 - enzyme binding GO:0042803 - protein homodimerization activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 862 Hs			1 735
+	Hs
		3362 A0A0S2Z4M1_HUMAN (1-862): 0: 1085: 90.37		TRIM1_HUMAN (1-735): 0: 599: 100.00
+	Hs
		181140 AXIN1_HUMAN (1-862): 0: 1232: 100.00		TRI42_HUMAN (24-422): 1.06e-72: 252: 22.87
+	Hs
		181167 AXIN1_HUMAN (1-862): 0: 1232: 100.00		TRI54_HUMAN (184-400): 6.86e-53: 188: 23.96
+	Hs
		181152 AXIN1_HUMAN (1-862): 0: 1232: 100.00		TRI11_HUMAN (16-269): 4.73e-23: 105: 16.54
+	Hs
		3351 A0A0S2Z4M1_HUMAN (1-862): 0: 1085: 90.37		TRI42_HUMAN (24-422): 1.06e-72: 252: 22.87
+	Hs
		181050 AXIN1_HUMAN (1-862): 0: 1232: 100.00		TRI27_HUMAN (16-326): 4.07e-19: 93.2: 15.48
+	Hs
		3338 A0A0S2Z4M1_HUMAN (1-862): 0: 1085: 90.37		TRI27_HUMAN (16-326): 4.07e-19: 93.2: 15.48
+	Hs
		1420539 RGS18_HUMAN (31-225): 3.67e-56: 195: 27.92		TRIM9_HUMAN (21-712): 2.35e-110: 352: 22.51
+	Hs
		889368 RGS6_HUMAN (31-228): 7.99e-62: 218: 18.91		TRI67_HUMAN (74-718): 5.72e-90: 300: 23.10
+	Hs
		223469 RGS10_HUMAN (84-232): 2.05e-46: 165: 31.54		TRI67_HUMAN (74-718): 5.72e-90: 300: 23.10