Interactor 1: RPB4 (O15514)
DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D) (RNA polymerase II 16 kDa subunit) (RPB16)
Gene: POLR2D

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 26186194, 26496610, 24981860, 33961781, 35271311, 28514442, 37071682, 10567706
Identification Methods affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb4~S1, RNA_pol_Rpb4~SHS2_Rpb7-N
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005665 - RNA polymerase II, core complex
GO:0006366 - transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 142
Hs

1 172
+ Dm
+ Sp
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024