Interactor 1: CLOCK (O15516)
Circadian locomoter output cycles protein kaput (hCLOCK) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 8) (bHLHe8)
Gene: CLOCK

Interactor 2: CIART (Q8N365)
Circadian-associated transcriptional repressor (ChIP-derived repressor of network oscillator) (Chrono) (Computationally highlighted repressor of the network oscillator)
Gene: CIART

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.500

The method score is based on:

Property Details
Experiments 24737000
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0032922 - circadian regulation of gene expression
GO:0045892 - negative regulation of DNA-templated transcription
GO:0070888 - E-box binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 846
Hs

1 385
+ Mm

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Last updated: 15 Jul 2024