Protein: TBR1
T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56)

Gene: TBR1
Organism: Homo sapiens
Interactions: 120
UniProt ID: Q16650

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001661 - conditioned taste aversion
GO:0001708 - cell fate specification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

885253

HXA1
Homeobox protein Hox-A1

1

20

High-throughput

0.698

High

168700

CSKP
Peripheral plasma membrane protein CASK

3

1

Small-scale

0.658

High

181517

TBXT
T-box transcription factor T

1

12

High-throughput

0.646

High

893657

MNX1
Motor neuron and pancreas homeobox protein 1

1

20

High-throughput

0.618

High

1005590

PITX1
Pituitary homeobox 1

1

9

High-throughput

0.618

High

1155961

ZFHX3
Zinc finger homeobox protein 3

1

4

High-throughput

0.618

High

1160865

ZFHX4
Zinc finger homeobox protein 4

1

6

High-throughput

0.618

High

1160892

NKX24
Homeobox protein Nkx-2.4

1

20

High-throughput

0.618

High

1160905

SATB2
DNA-binding protein SATB2

1

5

High-throughput

0.618

High

927322

ATX1
Ataxin-1

2

7

High-throughput

0.601

High

190067

FOXP2
Forkhead box protein P2

1

9

High-throughput

0.541

High

287934

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

1

High-throughput

0.541

High

582820

EZRI
Ezrin

2

1

High-throughput

0.521

High

143018

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.515

High

1087767

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.515

High

241816

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.515

High

422188

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.515

High

843598

HD
Huntingtin

1

1

High-throughput

0.515

High

563834

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

1160863

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

0

High-throughput

0.513

High

1160884

RMD5B
E3 ubiquitin-protein transferase RMND5B

1

0

High-throughput

0.513

High

474021

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.501

High

775847

HNF1B
Hepatocyte nuclear factor 1-beta

1

12

High-throughput

0.501

High

1133433

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.501

High

1160873

SP7
Transcription factor Sp7

1

9

High-throughput

0.500

High

791424

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

139005

BCL9
B-cell CLL/lymphoma 9 protein

1

13

High-throughput

0.479

High

154703

ARI1A
AT-rich interactive domain-containing protein 1A

1

12

High-throughput

0.479

High

158445

RFXK
DNA-binding protein RFXANK

1

1

High-throughput

0.479

High

161478

KMT2D
Histone-lysine N-methyltransferase 2D

1

7

High-throughput

0.479

High

174355

ZN609
Zinc finger protein 609

1

8

High-throughput

0.479

High

177464

ZN536
Zinc finger protein 536

1

3

High-throughput

0.479

High

177690

SMAD7
Mothers against decapentaplegic homolog 7

1

6

Small-scale

0.479

High

194571

KDM6A
Lysine-specific demethylase 6A

1

3

High-throughput

0.479

High

260021

BRD4
Bromodomain-containing protein 4

1

7

High-throughput

0.479

High

261412

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

4

High-throughput

0.479

High

277177

ZN217
Zinc finger protein 217

1

2

High-throughput

0.479

High

278363

NCOR1
Nuclear receptor corepressor 1

1

15

High-throughput

0.479

High

315641

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

331008

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.479

High

349104

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.479

High

505567

ATX1L
Ataxin-1-like

1

7

High-throughput

0.479

High

586304

ZEP1
Zinc finger protein 40

1

1

High-throughput

0.479

High

674181

BRD2
Bromodomain-containing protein 2

1

9

High-throughput

0.479

High

701157

PSB5
Proteasome subunit beta type-5

1

2

High-throughput

0.479

High

776076

SOX5
Transcription factor SOX-5

1

16

High-throughput

0.479

High

903171

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

14

High-throughput

0.479

High

907454

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.479

High

954819

PSA6
Proteasome subunit alpha type-6

1

1

High-throughput

0.479

High

1017428

FOXK1
Forkhead box protein K1

1

7

High-throughput

0.479

High

1047830

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

1047982

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

1048160

TLE4
Transducin-like enhancer protein 4

1

20

High-throughput

0.479

High

1061713

TLE5
TLE family member 5

1

20

High-throughput

0.479

High

1067397

EP300
Histone acetyltransferase p300

1

16

High-throughput

0.479

High

1130621

GSE1
Genetic suppressor element 1

1

1

High-throughput

0.479

High

1141144

BRD3
Bromodomain-containing protein 3

1

10

High-throughput

0.479

High

1145467

RBBP5
Retinoblastoma-binding protein 5

1

4

High-throughput

0.479

High

1150388

NCOA2
Nuclear receptor coactivator 2

1

7

High-throughput

0.479

High

1160851

ARI4B
AT-rich interactive domain-containing protein 4B

1

10

High-throughput

0.479

High

1160852

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

4

High-throughput

0.479

High

1160853

BRDT
Bromodomain testis-specific protein

1

13

High-throughput

0.479

High

1160859

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

13

High-throughput

0.479

High

1160861

BCOR
BCL-6 corepressor

1

4

High-throughput

0.479

High

1160862

PAXI1
PAX-interacting protein 1

1

6

High-throughput

0.479

High

1160864

LDB1
LIM domain-binding protein 1

1

1

High-throughput

0.479

High

1160866

BCL9L
B-cell CLL/lymphoma 9-like protein

1

12

High-throughput

0.479

High

1160868

FOXP4
Forkhead box protein P4

1

9

High-throughput

0.479

High

1160870

KMT2C
Histone-lysine N-methyltransferase 2C

1

10

High-throughput

0.479

High

1160871

ARI1B
AT-rich interactive domain-containing protein 1B

1

13

High-throughput

0.479

High

1160872

KDM2B
Lysine-specific demethylase 2B

1

3

High-throughput

0.479

High

1160874

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

1160875

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

4

High-throughput

0.479

High

1160877

MAML1
Mastermind-like protein 1

1

10

High-throughput

0.479

High

1160878

DPF1
Zinc finger protein neuro-d4

1

11

High-throughput

0.479

High

1160879

REQU
Zinc finger protein ubi-d4

1

14

High-throughput

0.479

High

1160880

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

10

High-throughput

0.479

High

1160881

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

1160882

SPDLY
Protein Spindly

1

1

High-throughput

0.479

High

1160883

ZN503
Zinc finger protein 503

1

2

High-throughput

0.479

High

1160885

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

8

High-throughput

0.479

High

1160886

CIC
Protein capicua homolog

1

16

High-throughput

0.479

High

1160888

PCGF1
Polycomb group RING finger protein 1

1

12

High-throughput

0.479

High

1160889

SSBP3
Single-stranded DNA-binding protein 3

1

6

High-throughput

0.479

High

1160893

ZN703
Zinc finger protein 703

1

4

High-throughput

0.479

High

1160897

HM20A
High mobility group protein 20A

1

15

High-throughput

0.479

High

1160898

TF7L2
Transcription factor 7-like 2

1

16

High-throughput

0.479

High

1160899

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

11

High-throughput

0.479

High

1160900

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

12

High-throughput

0.479

High

1160901

TRPS1
Zinc finger transcription factor Trps1

1

6

High-throughput

0.479

High

1160902

ZN608
Zinc finger protein 608

1

4

High-throughput

0.479

High

1160903

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

1

High-throughput

0.479

High

1160904

PRR12
Proline-rich protein 12

1

13

High-throughput

0.479

High

1160906

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

Small-scale

0.479

High

1160907

NCOR2
Nuclear receptor corepressor 2

1

10

High-throughput

0.479

High

1160908

NCOA3
Nuclear receptor coactivator 3

1

7

High-throughput

0.479

High

324901

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

555402

SKI
Ski oncogene

1

0

High-throughput

0.458

High

1122498

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

1160857

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1160858

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.458

High

1160876

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1160887

PYGO2
Pygopus homolog 2

1

0

High-throughput

0.458

High

1160890

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.458

High

1160891

TSYL2
Testis-specific Y-encoded-like protein 2

1

0

Small-scale

0.458

High

1160895

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

396208

ESR1
Estrogen receptor

1

7

High-throughput

0.445

High

429975

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

106013

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1126920

RBM39
RNA-binding protein 39

1

1

High-throughput

0.437

High

1160850

QSER1
Glutamine and serine-rich protein 1

1

12

High-throughput

0.437

High

1160854

ZMYM4
Zinc finger MYM-type protein 4

1

5

High-throughput

0.437

High

1160855

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.437

High

1160867

PRSR1
Proline and serine-rich protein 1

1

7

High-throughput

0.437

High

1160894

FBRS
Probable fibrosin-1

1

4

High-throughput

0.437

High

1160896

FBSL
Fibrosin-1-like protein

1

4

High-throughput

0.437

High

1160856

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.407

High

1160869

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1049158

RON
Macrophage-stimulating protein receptor

1

0

High-throughput

0.249

Low

1160860

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025