HitPredict

Interactor 1: CFLAR (O15519)
CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]
Gene: CFLAR

Interactor 2: GELS (P06396)
Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin)
Gene: GSN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25246592
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 782
+	Hs
		413862 CASP4_HUMAN (142-479): 9.69e-95: 293: 17.22		GELS_HUMAN (1-782): 0: 1207: 100.00
+	Hs
		413852 CASP3_HUMAN (209-479): 8.43e-89: 274: 22.53		GELS_HUMAN (1-782): 0: 1207: 100.00