Protein: TBXT
T-box transcription factor T (Brachyury protein) (Protein T)

Gene: TBXT
Organism: Homo sapiens
Interactions: 118
UniProt ID: O15178

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001707 - mesoderm formation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

181517

TBR1
T-box brain protein 1

1

12

High-throughput

0.646

High

181489

CUX1
Homeobox protein cut-like 1

1

8

High-throughput

0.618

High

181491

MNX1
Motor neuron and pancreas homeobox protein 1

1

20

High-throughput

0.618

High

181499

SATB1
DNA-binding protein SATB1

1

5

High-throughput

0.618

High

181532

ZFHX4
Zinc finger homeobox protein 4

1

6

High-throughput

0.618

High

181562

MIXL1
Homeobox protein MIXL1

1

20

Small-scale

0.618

High

181576

SIX4
Homeobox protein SIX4

1

12

High-throughput

0.618

High

181581

SATB2
DNA-binding protein SATB2

1

5

High-throughput

0.618

High

142720

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.578

High

181508

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.578

High

181484

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.561

High

181488

PYR1
Multifunctional protein CAD

1

1

High-throughput

0.500

High

181523

ZMYM4
Zinc finger MYM-type protein 4

1

5

High-throughput

0.489

High

181505

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.479

High

138950

BCL9
B-cell CLL/lymphoma 9 protein

1

13

High-throughput

0.479

High

154582

ARI1A
AT-rich interactive domain-containing protein 1A

1

12

High-throughput

0.479

High

161372

KMT2D
Histone-lysine N-methyltransferase 2D

1

7

High-throughput

0.479

High

174283

ZN609
Zinc finger protein 609

1

8

High-throughput

0.479

High

177420

ZN536
Zinc finger protein 536

1

3

High-throughput

0.479

High

180620

TIF1A
Transcription intermediary factor 1-alpha

1

11

High-throughput

0.479

High

181476

HDAC3
Histone deacetylase 3

1

7

High-throughput

0.479

High

181477

KDM6A
Lysine-specific demethylase 6A

1

3

High-throughput

0.479

High

181478

ZEB2
Zinc finger E-box-binding homeobox 2

1

3

High-throughput

0.479

High

181479

KDM1A
Lysine-specific histone demethylase 1A

1

6

High-throughput

0.479

High

181480

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

4

High-throughput

0.479

High

181481

CREST
Calcium-responsive transactivator

1

10

High-throughput

0.479

High

181482

NCOR1
Nuclear receptor corepressor 1

1

15

High-throughput

0.479

High

181483

WIZ
Protein Wiz

1

1

High-throughput

0.479

High

181485

ATX1L
Ataxin-1-like

1

7

High-throughput

0.479

High

181486

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

7

High-throughput

0.479

High

181487

ZEP1
Zinc finger protein 40

1

1

High-throughput

0.479

High

181490

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

181492

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

14

High-throughput

0.479

High

181493

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

14

High-throughput

0.479

High

181494

ATX1
Ataxin-1

1

7

High-throughput

0.479

High

181495

ATN1
Atrophin-1

1

16

High-throughput

0.479

High

181496

DCAF7
DDB1- and CUL4-associated factor 7

1

3

High-throughput

0.479

High

181498

SSBP2
Single-stranded DNA-binding protein 2

1

2

High-throughput

0.479

High

181500

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

181501

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

181502

TLE4
Transducin-like enhancer protein 4

1

20

High-throughput

0.479

High

181503

RING1
E3 ubiquitin-protein ligase RING1

1

13

High-throughput

0.479

High

181504

TLE5
TLE family member 5

1

20

High-throughput

0.479

High

181506

EP300
Histone acetyltransferase p300

1

16

High-throughput

0.479

High

181509

FOXC1
Forkhead box protein C1

1

6

High-throughput

0.479

High

181512

NCOA6
Nuclear receptor coactivator 6

1

14

High-throughput

0.479

High

181514

RBBP5
Retinoblastoma-binding protein 5

1

4

High-throughput

0.479

High

181515

SSXT
Protein SSXT

1

11

High-throughput

0.479

High

181516

NCOA2
Nuclear receptor coactivator 2

1

7

High-throughput

0.479

High

181519

ARI4B
AT-rich interactive domain-containing protein 4B

1

10

High-throughput

0.479

High

181520

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

4

High-throughput

0.479

High

181524

NIPBL
Nipped-B-like protein

1

5

High-throughput

0.479

High

181525

ZN746
Zinc finger protein 746

1

2

High-throughput

0.479

High

181526

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

13

High-throughput

0.479

High

181527

BCOR
BCL-6 corepressor

1

4

High-throughput

0.479

High

181528

PAXI1
PAX-interacting protein 1

1

6

High-throughput

0.479

High

181529

POGZ
Pogo transposable element with ZNF domain

1

3

High-throughput

0.479

High

181530

I2BP2
Interferon regulatory factor 2-binding protein 2

1

2

High-throughput

0.479

High

181531

LDB1
LIM domain-binding protein 1

1

1

High-throughput

0.479

High

181533

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

2

High-throughput

0.479

High

181534

HOMEZ
Homeobox and leucine zipper protein Homez

1

16

High-throughput

0.479

High

181535

YAF2
YY1-associated factor 2

1

3

High-throughput

0.479

High

181536

RYBP
RING1 and YY1-binding protein

1

3

High-throughput

0.479

High

181537

KMT2C
Histone-lysine N-methyltransferase 2C

1

10

High-throughput

0.479

High

181538

ARI1B
AT-rich interactive domain-containing protein 1B

1

13

High-throughput

0.479

High

181539

KDM2B
Lysine-specific demethylase 2B

1

3

High-throughput

0.479

High

181540

SMRC2
SWI/SNF complex subunit SMARCC2

1

14

High-throughput

0.479

High

181541

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

181543

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

4

High-throughput

0.479

High

181544

MAML1
Mastermind-like protein 1

1

10

High-throughput

0.479

High

181545

DPF1
Zinc finger protein neuro-d4

1

11

High-throughput

0.479

High

181546

REQU
Zinc finger protein ubi-d4

1

14

High-throughput

0.479

High

181547

CBP
CREB-binding protein

1

15

High-throughput

0.479

High

181548

SMRC1
SWI/SNF complex subunit SMARCC1

1

9

High-throughput

0.479

High

181549

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

10

High-throughput

0.479

High

181551

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

8

High-throughput

0.479

High

181552

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

2

High-throughput

0.479

High

181553

CIC
Protein capicua homolog

1

16

High-throughput

0.479

High

181554

MINT
Msx2-interacting protein

1

9

High-throughput

0.479

High

181555

ARI3A
AT-rich interactive domain-containing protein 3A

1

9

High-throughput

0.479

High

181556

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

4

High-throughput

0.479

High

181557

PCGF1
Polycomb group RING finger protein 1

1

12

High-throughput

0.479

High

181559

SSBP3
Single-stranded DNA-binding protein 3

1

6

High-throughput

0.479

High

181560

SP130
Histone deacetylase complex subunit SAP130

1

7

High-throughput

0.479

High

181561

ING2
Inhibitor of growth protein 2

1

5

High-throughput

0.479

High

181563

FOXP1
Forkhead box protein P1

1

8

High-throughput

0.479

High

181564

ZN644
Zinc finger protein 644

1

3

High-throughput

0.479

High

181565

ZN703
Zinc finger protein 703

1

4

High-throughput

0.479

High

181569

HM20A
High mobility group protein 20A

1

15

High-throughput

0.479

High

181570

TF7L2
Transcription factor 7-like 2

1

16

High-throughput

0.479

High

181571

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

11

High-throughput

0.479

High

181572

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

12

High-throughput

0.479

High

181573

RCOR3
REST corepressor 3

1

13

High-throughput

0.479

High

181574

TCF20
Transcription factor 20

1

4

High-throughput

0.479

High

181575

TRPS1
Zinc finger transcription factor Trps1

1

6

High-throughput

0.479

High

181577

ING1
Inhibitor of growth protein 1

1

5

High-throughput

0.479

High

181578

RCOR1
REST corepressor 1

1

17

High-throughput

0.479

High

181579

ZN608
Zinc finger protein 608

1

4

High-throughput

0.479

High

181580

PRR12
Proline-rich protein 12

1

13

High-throughput

0.479

High

181582

ZN148
Zinc finger protein 148

1

3

High-throughput

0.479

High

181583

ZN281
Zinc finger protein 281

1

3

High-throughput

0.479

High

181584

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

1

High-throughput

0.479

High

181585

NCOR2
Nuclear receptor corepressor 2

1

10

High-throughput

0.479

High

181586

NCOA3
Nuclear receptor coactivator 3

1

7

High-throughput

0.479

High

181497

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.458

High

181507

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.458

High

181510

GPS2
G protein pathway suppressor 2

1

0

High-throughput

0.458

High

181511

CUL3
Cullin-3

1

0

High-throughput

0.458

High

181522

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

0

High-throughput

0.458

High

181542

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

181550

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.458

High

181558

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

0

High-throughput

0.458

High

181568

SHCAF
SIN3-HDAC complex-associated factor

1

0

High-throughput

0.458

High

181513

GSE1
Genetic suppressor element 1

1

1

High-throughput

0.437

High

181518

QSER1
Glutamine and serine-rich protein 1

1

12

High-throughput

0.437

High

181566

FBRS
Probable fibrosin-1

1

4

High-throughput

0.437

High

181567

FBSL
Fibrosin-1-like protein

1

4

High-throughput

0.437

High

181521

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025