Interactor 1: TPSN (O15533)
Tapasin (TPN) (TPSN) (NGS-17) (TAP-associated protein) (TAP-binding protein)
Gene: TAPBP

Interactor 2: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 11823531, 17170699
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, disulfide bond

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002502 - peptide antigen assembly with MHC class I protein complex
GO:0005783 - endoplasmic reticulum
GO:0042824 - MHC class I peptide loading complex
GO:0061779 - Tapasin-ERp57 complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 448
Hs

1 505
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024