HitPredict

Interactor 1: METK1 (O17680)
Probable S-adenosylmethionine synthase 1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1)
Gene: sams-1

Interactor 2: METK3 (P50305)
Probable S-adenosylmethionine synthase 3 (AdoMet synthase 3) (EC 2.5.1.6) (Methionine adenosyltransferase 3) (MAT 3)
Gene: sams-3

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.723

The method score is based on:

Property Details
Experiments 19123269
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains S-AdoMet_synt_C~S-AdoMet_synt_C, S-AdoMet_synt_C~S-AdoMet_synt_M, S-AdoMet_synt_C~S-AdoMet_synt_N, S-AdoMet_synt_M~S-AdoMet_synt_M, S-AdoMet_synt_M~S-AdoMet_synt_N, S-AdoMet_synt_N~S-AdoMet_synt_N
Common GO terms GO:0004478 - methionine adenosyltransferase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006556 - S-adenosylmethionine biosynthetic process
GO:0006730 - one-carbon metabolic process
and 1 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 403
Ce

1 404
+ Ce
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Rn
+ Zm
+ Sc
+ Sc
+ Sp
+ Sc
+ Dm
+ Ec
+ Pf
+ Cj

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024