HitPredict

Interactor 1: IPO8 (O15397)
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)
Gene: IPO8

Interactor 2: PAXI (P49023)
Paxillin
Gene: PXN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1037 Hs			1 591
+	Hs
		189284 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZN160_HUMAN (164-529): 2.85e-90: 297: 10.50
+	Hs
		189202 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZN534_HUMAN (164-527): 2.08e-86: 284: 9.50
+	Hs
		189215 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZNF34_HUMAN (134-586): 2.46e-82: 270: 12.22
+	Hs
		334814 IPO7_HUMAN (1-1031): 0: 816: 64.57		ZN534_HUMAN (164-527): 2.08e-86: 284: 9.50
+	Hs
		189283 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZN287_HUMAN (164-468): 5.52e-73: 250: 7.33
+	Hs
		334937 IPO7_HUMAN (1-1031): 0: 816: 64.57		ZN180_HUMAN (236-589): 1.57e-62: 220: 9.07
+	Hs
		334771 IPO7_HUMAN (1-1031): 0: 816: 64.57		ZN267_HUMAN (276-591): 2.1e-54: 198: 8.37
+	Hs
		189238 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZN480_HUMAN (164-380): 1.33e-34: 139: 8.41
+	Hs
		334711 IPO7_HUMAN (1-1031): 0: 816: 64.57		LIMS1_HUMAN (346-529): 3.49e-43: 159: 32.97
+	Hs
		189217 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZN567_HUMAN (164-381): 2.94e-33: 136: 5.73
+	Hs
		334834 IPO7_HUMAN (1-1031): 0: 816: 64.57		ZN567_HUMAN (164-381): 2.94e-33: 136: 5.73
+	Hs
		189151 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZN543_HUMAN (180-365): 6.48e-26: 114: 8.07
+	Hs
		189180 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZN484_HUMAN (401-589): 8.34e-25: 111: 10.47
+	Hs
		189192 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZFP1_HUMAN (268-414): 6.28e-20: 94.2: 6.71
+	Hs
		334791 IPO7_HUMAN (1-1031): 0: 816: 64.57		ZN484_HUMAN (401-589): 8.34e-25: 111: 10.47
+	Hs
		189100 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZNF3_HUMAN (506-591): 2.14e-18: 90: 14.74
+	Hs
		189101 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZNF7_HUMAN (164-352): 1.18e-17: 88.8: 4.48
+	Hs
		334802 IPO7_HUMAN (1-1031): 0: 816: 64.57		ZFP1_HUMAN (268-414): 6.28e-20: 94.2: 6.71
+	Hs
		189226 IPO8_HUMAN (1-1037): 0: 836: 100.00		ZN565_HUMAN (191-380): 8.04e-09: 60.3: 8.95
+	Hs
		334845 IPO7_HUMAN (1-1031): 0: 816: 64.57		ZN565_HUMAN (191-380): 8.04e-09: 60.3: 8.95