HitPredict

Interactor 1: PHB2 (O35129)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity)
Gene: PHB2

Interactor 2: CAV3 (P51637)
Caveolin-3 (M-caveolin)
Gene: CAV3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24952909
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0032991 - protein-containing complex GO:0060762 - regulation of branching involved in mammary gland duct morphogenesis
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 299 Mm			1 151
+	Hs
		974990 PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00		CAV1_HUMAN (8-150): 4.14e-79: 233: 65.73
+	Hs
		848562 PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00		CAV2_HUMAN (26-150): 3.46e-56: 174: 37.60
+	Mm
		848605 PHB1_MOUSE (22-280): 6.64e-86: 260: 51.54		CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00
+	Hs
		718774 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		CAV1_HUMAN (8-150): 4.14e-79: 233: 65.73
+	Hs
		646175 STOM_HUMAN (1-286): 2.42e-84: 256: 17.93		CAV1_HUMAN (8-150): 4.14e-79: 233: 65.73
+	Mm
		848585 STOM_MOUSE (1-286): 5.6e-79: 242: 16.90		CAV3_MOUSE (1-151): 1.82e-79: 233: 100.00
+	Mm
		835147 STML3_MOUSE (4-297): 1.61e-71: 224: 17.45		CAV1_MOUSE (2-150): 1.96e-78: 231: 65.10
+	Hs
		718637 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		CAV2_HUMAN (26-150): 3.46e-56: 174: 37.60