HitPredict

Interactor 1: NEB2 (O35274)
Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130)
Gene: Ppp1r9b

Interactor 2: PP1G (P63088)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: Ppp1cc

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	20124353, 18216290, 10391935
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Metallophos~PDZ, PDZ~STPPase_N, Metallophos~PDZ_5, PDZ_5~STPPase_N
Common GO terms	GO:0005737 - cytoplasm GO:0008157 - protein phosphatase 1 binding GO:0043197 - dendritic spine GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 817 Rn			1 323
+	Mm
		926545 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		PP1G_MOUSE (1-323): 0: 601: 100.00
+	Hs
		737997 NEB2_HUMAN (1-817): 1.43e-108: 353: 94.74		PP1G_HUMAN (1-323): 0: 601: 99.69
+	Rn
		192519 NEB2_RAT (1-817): 4.47e-115: 370: 100.00		PP1A_RAT (1-323): 0: 578: 90.66
+	Mm
		906288 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		PP1A_MOUSE (1-323): 0: 578: 90.36
+	Hs
		738120 NEB1_HUMAN (1-817): 1.44e-101: 340: 46.26		PP1G_HUMAN (1-323): 0: 601: 99.69
+	Hs
		906098 NEB2_HUMAN (1-817): 1.43e-108: 353: 94.74		PP1A_HUMAN (1-323): 0: 578: 90.66
+	Rn
		192520 NEB2_RAT (1-817): 4.47e-115: 370: 100.00		PP1B_RAT (1-322): 0: 559: 86.89
+	Mm
		906654 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		PP1B_MOUSE (1-322): 0: 559: 86.89
+	Rn
		193534 NEB1_RAT (1-817): 4.73e-95: 323: 45.86		PP1G_RAT (1-323): 0: 601: 100.00
+	Hs
		906197 NEB1_HUMAN (1-817): 1.44e-101: 340: 46.26		PP1A_HUMAN (1-323): 0: 578: 90.66
+	Hs
		906570 NEB2_HUMAN (1-817): 1.43e-108: 353: 94.74		PP1B_HUMAN (1-322): 0: 559: 86.89
+	Hs
		906629 NEB1_HUMAN (1-817): 1.44e-101: 340: 46.26		PP1B_HUMAN (1-322): 0: 559: 86.89
+	Rn
		193533 NEB1_RAT (1-817): 4.73e-95: 323: 45.86		PP1B_RAT (1-322): 0: 559: 86.89
+	Mm
		915331 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		PP2AB_MOUSE (8-312): 4.54e-178: 496: 46.73
+	Hs
		905921 DLG2_HUMAN (65-755): 1.3e-65: 237: 12.19		PP1A_HUMAN (1-323): 0: 578: 90.66
+	Mm
		906274 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		PP1A_MOUSE (1-323): 0: 578: 90.36
+	Hs
		737994 ERBIN_HUMAN (14-583): 2.28e-42: 169: 13.46		PP1G_HUMAN (1-323): 0: 601: 99.69
+	Mm
		906652 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		PP1B_MOUSE (1-322): 0: 559: 86.89
+	Hs
		906094 ERBIN_HUMAN (14-583): 2.28e-42: 169: 13.46		PP1A_HUMAN (1-323): 0: 578: 90.66
+	Mm
		915328 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		PP2AB_MOUSE (8-312): 4.54e-178: 496: 46.73