HitPredict

Interactor 1: PSDE (O35593)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (MAD1)
Gene: Psmd14

Interactor 2: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.696

Property	Details
Experiments	28190767, 29676259
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Mm			1 734
+	Mm
		193512 CSN5_MOUSE (1-305): 4.65e-83: 255: 28.35		UBC_MOUSE (1-734): 0: 912: 100.00
+	Hs
		130705 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476142 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		176926 EIF3H_HUMAN (23-298): 5.55e-55: 183: 21.05		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		317703 STABP_HUMAN (17-199): 5.28e-44: 157: 17.84		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		476192 STALP_HUMAN (18-208): 4.08e-42: 152: 18.65		UBC_HUMAN (77-724): 0: 790: 97.22
+	Sc
		477336 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99
+	At
		1092172 PSDE_ARATH (1-309): 1.07e-109: 322: 79.61		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	Sc
		477501 CSN5_YEAST (14-282): 4.39e-45: 160: 24.11		UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99
+	At
		1091793 CSN5A_ARATH (2-303): 1.72e-80: 249: 29.78		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1091965 EIF3H_ARATH (7-304): 4.37e-72: 227: 18.61		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1091969 PSD7B_ARATH (15-256): 1.76e-49: 168: 18.43		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	Hs
		130837 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00
+	At
		188941 PSD7A_ARATH (15-256): 5.45e-49: 167: 18.04		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1091838 AMSH1_ARATH (30-213): 1.94e-45: 162: 17.39		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		137953 EIF3F_ARATH (17-277): 2.76e-46: 159: 19.39		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	Hs
		130693 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69
+	Hs
		130704 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70
+	Hs
		317702 STABP_HUMAN (17-199): 5.28e-44: 157: 17.84		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70
+	Hs
		474952 BRCC3_HUMAN (32-188): 1e-41: 148: 25.79		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70