HitPredict

Interactor 1: FYB1 (O35601)
FYN-binding protein 1 (Adhesion and degranulation promoting adaptor protein) (ADAP) (FYB-120/130) (p120/p130) (FYN-T-binding protein) (SLAP-130) (SLP-76-associated phosphoprotein)
Gene: FYB1

Interactor 2: LCK (P06240)
Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12681493
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~SH3_2, SH3_1~SH3_2
Common GO terms	GO:0005829 - cytosol GO:0044877 - protein-containing complex binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 819 Mm			1 509
+	Mm
		193090 FYB1_MOUSE (1-819): 2.37e-92: 310: 100.00		FYN_MOUSE (1-507): 0: 590: 53.85
+	Mm
		193089 FYB1_MOUSE (1-819): 2.37e-92: 310: 100.00		LYN_MOUSE (1-509): 0: 567: 62.72
+	Hs
		167737 FYB1_HUMAN (1-819): 5.4e-72: 253: 70.40		FYN_HUMAN (1-507): 0: 591: 54.03
+	Hs
		167735 FYB1_HUMAN (1-819): 5.4e-72: 253: 70.40		ABL1_HUMAN (34-506): 1.69e-167: 505: 40.54
+	Hs
		203198 SYNJ1_HUMAN (273-667): 1.53e-10: 67.4: 8.27		LCK_HUMAN (1-509): 0: 634: 96.86
+	Hs
		411582 MUC1_HUMAN (14-519): 3.12e-09: 63: 13.24		LCK_HUMAN (1-509): 0: 634: 96.86
+	Hs
		433701 ANK2_HUMAN (65-703): 2.74e-22: 105: 13.21		LYN_HUMAN (1-509): 0: 566: 63.37
+	Hs
		433853 MICA3_HUMAN (3-733): 5.91e-21: 101: 13.15		LYN_HUMAN (1-509): 0: 566: 63.37
+	Hs
		297808 K0754_HUMAN (6-528): 3.19e-20: 99: 8.56		LYN_HUMAN (1-509): 0: 566: 63.37
+	Hs
		433954 PRAM_HUMAN (16-570): 1.35e-13: 76.7: 11.47		LYN_HUMAN (1-509): 0: 566: 63.37
+	Hs
		522830 UBP8_HUMAN (268-693): 9.99e-10: 64.6: 16.48		SRC_HUMAN (2-507): 0: 576: 54.13
+	Hs
		523118 CIC_HUMAN (29-714): 1.99e-09: 63.6: 8.66		SRC_HUMAN (2-507): 0: 576: 54.13
+	Hs
		522749 MUC1_HUMAN (14-519): 3.12e-09: 63: 13.24		SRC_HUMAN (2-507): 0: 576: 54.13
+	Hs
		433560 MUC1_HUMAN (14-519): 3.12e-09: 63: 13.24		LYN_HUMAN (1-509): 0: 566: 63.37
+	Hs
		152571 KMT2D_HUMAN (163-772): 1.52e-09: 64.3: 9.02		ABL1_HUMAN (34-506): 1.69e-167: 505: 40.54
+	Hs
		337335 MUC1_HUMAN (14-519): 3.12e-09: 63: 13.24		ABL1_HUMAN (34-506): 1.69e-167: 505: 40.54
+	Hs
		782820 CIC_HUMAN (29-714): 1.99e-09: 63.6: 8.66		CSK_HUMAN (59-500): 2.05e-174: 500: 37.80