Interactor 1: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2
Interactor 2: RNF5 (Q99942)
E3 ubiquitin-protein ligase RNF5 (EC 2.3.2.27) (RING finger protein 5) (Ram1 homolog) (HsRma1)
Gene: RNF5
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.82 | 1.00 | 0.911 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, 19549727, unassigned1304 |
| Identification Methods | two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UQ_con~zf-C3HC4_3 |
| Common GO terms | GO:0004842 - ubiquitin-protein transferase activity GO:0070534 - protein K63-linked ubiquitination GO:0070936 - protein K48-linked ubiquitination |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
