HitPredict

Interactor 1: SOCS1 (O35716)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1)
Gene: SOCS1

Interactor 2: INSR (P15208)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15169905
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~fn3, PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0005159 - insulin-like growth factor receptor binding
GO:0019901 - protein kinase binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 212
Mm

1 1372
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024