HitPredict

Interactor 1: SOCS1 (O35716)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1)
Gene: SOCS1

Interactor 2: INAR1 (P33896)
Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Type I interferon receptor 1)
Gene: Ifnar1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21757742
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019221 - cytokine-mediated signaling pathway
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 212 Mm			1 590
+	Hs
		181792 SOCS1_HUMAN (1-212): 2.59e-45: 151: 94.81		INAR1_HUMAN (1-540): 6.38e-107: 334: 49.27
+	Hs
		566001 P85A_HUMAN (76-181): 2.01e-17: 81.7: 23.59		INAR1_HUMAN (1-540): 6.38e-107: 334: 49.27
+	Hs
		411959 FYN_HUMAN (69-195): 3.04e-36: 134: 18.98		PTPRF_HUMAN (1-517): 4.79e-56: 207: 13.00
+	Hs
		181786 SOCS1_HUMAN (1-212): 2.59e-45: 151: 94.81		INGR1_HUMAN (2-224): 4.03e-46: 171: 16.25
+	Hs
		1267452 P55G_HUMAN (38-172): 5.2e-23: 97.5: 13.99		I20RA_HUMAN (20-293): 3.95e-63: 219: 22.34
+	Mm
		193339 SOCS1_MOUSE (1-212): 3.72e-50: 163: 100.00		INGR1_MOUSE (26-347): 5.59e-39: 151: 15.00
+	Hs
		655495 P85A_HUMAN (76-181): 2.01e-17: 81.7: 23.59		I20RA_HUMAN (20-293): 3.95e-63: 219: 22.34
+	Hs
		297883 NCK1_HUMAN (4-175): 1.37e-40: 143: 18.39		NFASC_HUMAN (2-557): 2.97e-22: 103: 10.09
+	Dm
		53796 ABL_DROME (7-192): 1.12e-36: 137: 15.15		A1Z921_DROME (28-450): 6.56e-24: 109: 14.48
+	Mm
		56907 FYN_MOUSE (69-195): 3.04e-36: 134: 18.98		PTPRF_MOUSE (99-526): 6.28e-23: 106: 9.03
+	Hs
		147398 SOCS3_HUMAN (40-208): 2.32e-42: 144: 27.27		IL6RB_HUMAN (173-434): 2.66e-19: 94.3: 16.73
+	Hs
		297881 FYN_HUMAN (69-195): 3.04e-36: 134: 18.98		NFASC_HUMAN (2-557): 2.97e-22: 103: 10.09
+	Hs
		412016 FYN_HUMAN (69-195): 3.04e-36: 134: 18.98		PTPRD_HUMAN (197-587): 8.09e-21: 99.7: 9.55
+	Hs
		234472 NCK1_HUMAN (4-175): 1.37e-40: 143: 18.39		DSCAM_HUMAN (305-554): 7.88e-15: 80.4: 9.13
+	Hs
		557632 NCK1_HUMAN (4-175): 1.37e-40: 143: 18.39		DCC_HUMAN (28-415): 1.58e-13: 76.1: 14.39
+	Mm
		193384 SOCS3_MOUSE (38-208): 4.45e-43: 146: 27.35		IL6RB_MOUSE (4-214): 2.49e-09: 62.2: 12.33
+	Hs
		655246 P85A_HUMAN (76-181): 2.01e-17: 81.7: 23.59		IL6RB_HUMAN (173-434): 2.66e-19: 94.3: 16.73