HitPredict

Interactor 1: SOCS3 (O35718)
Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (Protein EF-10)
Gene: SOCS3

Interactor 2: NCK1 (Q99M51)
SH2/SH3 adapter protein Nck1 (Cytoplasmic protein Nck1) (NCK adapter protein 1) (Nck-1)
Gene: NCK1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15173187
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, SH2~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0046627 - negative regulation of insulin receptor signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 225
Mm

1 377
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024