HitPredict

Interactor 1: DHX15 (O43143)
ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15) (Splicing factor Prp43) (hPrp43)
Gene: DHX15

Interactor 2: RBM5 (P52756)
RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9)
Gene: RBM5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 22365833, 22569250, 24304693
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains G-patch~HA2, G-patch~Helicase_C, G-patch~OB_NTP_bind
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 795
Hs

1 815
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+ At
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024