Protein: KLHL5
Kelch-like protein 5

Gene: KLHL5
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q96PQ7

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0015630 - microtubule cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114054

CUL3
Cullin-3

8

20

Small-scale

0.962

High

1399937

KLHL1
Kelch-like protein 1

2

18

High-throughput

0.776

High

1399934

KLHL4
Kelch-like protein 4

2

18

High-throughput

0.737

High

1371614

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

7

High-throughput

0.647

High

1399932

KLHL5
Kelch-like protein 5

1

17

High-throughput

0.618

High

1358238

SKA2
Spindle and kinetochore-associated protein 2

2

0

High-throughput

0.576

High

1399938

SPHK1
Sphingosine kinase 1

1

1

Small-scale

0.549

High

1399933

TRIM2
Tripartite motif-containing protein 2

1

7

High-throughput

0.536

High

405532

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.508

High

952295

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

9

High-throughput

0.508

High

1399935

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

9

High-throughput

0.508

High

1160553

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

869784

MTR1A
Melatonin receptor type 1A

1

3

High-throughput

0.481

High

1141876

EEA1
Early endosome antigen 1

1

5

High-throughput

0.479

High

651411

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

1110540

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

2

High-throughput

0.445

High

372888

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

775269

FUS
RNA-binding protein FUS

1

1

High-throughput

0.437

High

855502

ATRX
Transcriptional regulator ATRX

1

2

High-throughput

0.437

High

1256650

S31E1
Spermatogenesis-associated protein 31E1

1

1

High-throughput

0.437

High

1399936

RESF1
Retroelement silencing factor 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025