HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031175 - neuron projection development
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 758
+	Mm
		498051 SERA_MOUSE (1-533): 0: 684: 94.56		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		197305 SERA_HUMAN (1-533): 0: 667: 100.00		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		496669 CTBP2_HUMAN (21-383): 8.27e-123: 369: 29.10		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496961 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		292158 CTBP1_MOUSE (1-384): 7.07e-121: 364: 28.89		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		1032408 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		1032721 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19