Interactor 1: IRAK2 (O43187)
Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)
Gene: IRAK2
Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.755 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10383454, 9374458, 33799071, 17878161, 21903422, 26250868, 28514442, 33961781, 21988832 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002755 - MyD88-dependent toll-like receptor signaling pathway GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 8 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
