Protein: 6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1 (EC 1.1.1.44)

Gene: 6PGD1, GND1
Organism: Saccharomyces cerevisiae S288C
Interactions: 110
UniProt ID: P38720

Gene Ontology (top 5):
GO:0004616 - phosphogluconate dehydrogenase (decarboxylating) activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0008114 - phosphogluconate 2-dehydrogenase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

753232

6PGD2
6-phosphogluconate dehydrogenase, decarboxylating 2

2

4

High-throughput

0.776

High

366237

HSP82
ATP-dependent molecular chaperone HSP82

3

1

High-throughput

0.658

High

628015

SIS1
Protein SIS1

3

1

High-throughput

0.643

High

753225

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

0

High-throughput

0.613

High

753203

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

4

Small-scale

0.575

High

511185

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.571

High

493878

HSP72
Heat shock protein SSA2

2

3

High-throughput

0.552

High

753239

RAGAB
GTP-binding protein GTR1

2

0

Small-scale

0.551

High

567969

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

614638

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.536

High

753214

HAT2
Histone acetyltransferase type B subunit 2

1

1

High-throughput

0.536

High

753240

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

High-throughput

0.536

High

753241

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

420563

SPT2
Protein SPT2

1

0

High-throughput

0.513

High

753233

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

753237

EF3B
Elongation factor 3B

1

0

High-throughput

0.513

High

565576

PHO85
Cyclin-dependent protein kinase PHO85

1

2

High-throughput

0.501

High

753213

RSP5
E3 ubiquitin-protein ligase RSP5

1

3

High-throughput

0.501

High

579419

GBB
Guanine nucleotide-binding protein subunit beta

1

1

High-throughput

0.500

High

753251

IMH1
Golgin IMH1

1

1

High-throughput

0.500

High

753205

ARO9
Aromatic amino acid aminotransferase 2

1

0

High-throughput

0.493

High

678739

RAD16
DNA repair protein RAD16

1

2

High-throughput

0.489

High

753230

KIP3
Kinesin-like protein KIP3

1

2

High-throughput

0.489

High

753243

UTP17
NET1-associated nuclear protein 1

1

2

High-throughput

0.489

High

753248

ERB1
Ribosome biogenesis protein ERB1

1

1

High-throughput

0.489

High

753249

SEN15
tRNA-splicing endonuclease subunit SEN15

1

1

High-throughput

0.489

High

587308

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

Small-scale

0.480

High

753228

ENT3
Epsin-3

1

0

Small-scale

0.480

High

368024

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.479

High

704334

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.479

High

753211

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.479

High

342713

ENO1
Enolase 1

1

2

High-throughput

0.479

High

342920

ENO2
Enolase 2

1

2

High-throughput

0.479

High

425931

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

543678

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

621166

FPS1
Glycerol uptake/efflux facilitator protein

1

3

High-throughput

0.479

High

680678

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

696315

PP12
Serine/threonine-protein phosphatase PP1-2

1

1

High-throughput

0.479

High

705131

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

737158

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.479

High

753235

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

2

High-throughput

0.479

High

753244

ESP1
Separin

1

1

High-throughput

0.479

High

753246

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

340667

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

343385

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

375379

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

389278

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

404333

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.458

High

413486

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

421762

KAD2
Adenylate kinase

1

0

High-throughput

0.458

High

423522

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.458

High

482245

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

537408

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

540573

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

542677

TAL1
Transaldolase

1

0

High-throughput

0.458

High

613806

TKT1
Transketolase 1

1

0

High-throughput

0.458

High

688223

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

701772

YPT7
Ypt/Rab-type GTPase YPT7

1

0

Small-scale

0.458

High

703607

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

729892

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

753204

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

753207

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

753209

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

753212

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

753216

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

753221

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.458

High

753226

DUG1
Cys-Gly metallodipeptidase DUG1

1

0

High-throughput

0.458

High

753231

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

753236

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

753245

COFI
Cofilin

1

0

High-throughput

0.458

High

753252

SGO1
Shugoshin

1

0

High-throughput

0.458

High

753255

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

703206

PRP40
Pre-mRNA-processing protein PRP40

1

2

High-throughput

0.457

High

753256

YP150
Putative serine/threonine-protein kinase YPL150W

1

1

High-throughput

0.457

High

550024

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.457

High

584727

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.457

High

707333

PEX6
Peroxisomal ATPase PEX6

1

1

High-throughput

0.457

High

753227

YJ66
Uncharacterized oxidoreductase YJR096W

1

2

High-throughput

0.457

High

586401

PRP6
Pre-mRNA-splicing factor 6

1

1

High-throughput

0.457

High

753229

SEH1
Nucleoporin SEH1

1

1

High-throughput

0.457

High

491109

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

645201

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.445

High

753217

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

753218

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.445

High

753222

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.439

High

753242

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.439

High

753210

RBG1
Ribosome-interacting GTPase 1

1

0

High-throughput

0.438

High

753234

IST1
Vacuolar protein sorting-associated protein IST1

1

0

High-throughput

0.438

High

753238

ARP4
Actin-related protein 4

1

1

High-throughput

0.437

High

358047

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.426

High

645423

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.426

High

753208

ATC2
Calcium-transporting ATPase 2

1

1

High-throughput

0.417

High

753223

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.407

High

753215

SHO1
High osmolarity signaling protein SHO1

1

0

Small-scale

0.296

High

429695

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.279

Low

640314

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.279

Low

753206

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.279

Low

753219

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

0

High-throughput

0.261

Low

753250

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.261

Low

701209

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

474344

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

606633

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

662133

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

701415

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

753224

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.249

Low

753247

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

753253

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

753254

FLC1
Flavin carrier protein 1

1

0

High-throughput

0.238

Low

753220

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024