HitPredict

Interactor 1: PRS8 (O18413)
26S proteasome regulatory subunit 8
Gene: Rpt6

Interactor 2: ADRM1 (Q7K2G1)
Proteasomal ubiquitin receptor ADRM1 homolog (Regulatory particle non-ATPase 13 protein) (p42E)
Gene: Rpn13

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005838 - proteasome regulatory particle GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 405 Dm			1 389
+	Dm
		874970 PRS4_DROME (18-395): 6.2e-138: 402: 46.30		ADRM1_DROME (1-389): 8.14e-156: 446: 100.00
+	Dm
		1265217 Q9W414_DROME (15-402): 1.76e-124: 367: 45.62		ADRM1_DROME (1-389): 8.14e-156: 446: 100.00
+	Dm
		1265200 Q9V405_DROME (8-398): 3.82e-123: 364: 40.56		ADRM1_DROME (1-389): 8.14e-156: 446: 100.00
+	Dm
		1265189 Q7KMQ0_DROME (58-391): 2.17e-116: 347: 53.69		ADRM1_DROME (1-389): 8.14e-156: 446: 100.00
+	Hs
		968934 PRS8_HUMAN (5-405): 2.97e-131: 384: 92.77		ADRM1_HUMAN (12-361): 5.74e-130: 380: 38.34
+	Hs
		975410 PRS10_HUMAN (19-402): 1.1e-126: 372: 46.88		ADRM1_HUMAN (12-361): 5.74e-130: 380: 38.34
+	Hs
		968713 PRS4_HUMAN (18-395): 7.43e-125: 369: 47.35		ADRM1_HUMAN (12-361): 5.74e-130: 380: 38.34
+	Hs
		69437 A8K2M0_HUMAN (1-398): 4.23e-121: 359: 38.59		ADRM1_HUMAN (12-361): 5.74e-130: 380: 38.34
+	Hs
		851329 PRS6B_HUMAN (1-398): 4.23e-121: 359: 38.59		ADRM1_HUMAN (12-361): 5.74e-130: 380: 38.34
+	Hs
		778690 PRS7_HUMAN (83-391): 1.84e-116: 348: 56.63		ADRM1_HUMAN (12-361): 5.74e-130: 380: 38.34