Interactor 1: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7
Interactor 2: PPM1B (O75688)
Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta)
Gene: PPM1B
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.61 | 0.60 | 0.608 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11104763 |
| Identification Methods | affinity chromatography technology, pull down, in gel phosphatase assay, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, dephosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000287 - magnesium ion binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
