HitPredict

Interactor 1: WIPF1 (O43516)
WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19531213
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 503 Hs			1 665
+	Hs
		166055 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		1285221 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		166060 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		1356881 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		206680 WIPF1_HUMAN (1-503): 1.19e-30: 126: 100.00		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		206685 WIPF1_HUMAN (1-503): 1.19e-30: 126: 100.00		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		166030 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		557823 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		166042 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		924943 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Mm
		1225105 WIPF1_MOUSE (14-503): 4.22e-26: 112: 85.13		NCK1_MOUSE (104-421): 1.23e-32: 131: 15.93
+	Hs
		206699 WIPF1_HUMAN (1-503): 1.19e-30: 126: 100.00		ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30
+	Hs
		166056 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30
+	Hs
		166049 SYNJ2_HUMAN (11-462): 6.97e-28: 120: 15.62		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Hs
		206669 WIPF1_HUMAN (1-503): 1.19e-30: 126: 100.00		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Hs
		275240 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		GRAP2_HUMAN (1-56): 2.18e-17: 85.8: 32.14
+	Hs
		209187 ASAP1_HUMAN (12-437): 1.91e-27: 118: 19.59		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Hs
		209071 TGO1_HUMAN (137-399): 6.75e-26: 114: 26.67		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Hs
		206690 WIPF1_HUMAN (1-503): 1.19e-30: 126: 100.00		SH3R1_HUMAN (241-599): 5.37e-12: 71.2: 13.28
+	Hs
		209038 SOS1_HUMAN (134-459): 8.01e-24: 107: 16.77		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77