HitPredict

Interactor 1: CHM2A (O43633)
Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1)
Gene: CHMP2A

Interactor 2: STABP (O95630)
STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase)
Gene: STAMBP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	17159328, 28514442, 33961781, 16760479, 16730941
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019904 - protein domain specific binding GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 424
+	Hs
		317780 CHMP3_HUMAN (4-220): 3.75e-46: 154: 25.11		STABP_HUMAN (1-424): 0: 605: 100.00
+	Hs
		317769 CHM1A_HUMAN (21-220): 2.15e-37: 130: 24.00		STABP_HUMAN (1-424): 0: 605: 100.00
+	Hs
		317736 CHM1B_HUMAN (22-222): 2.58e-35: 125: 27.86		STABP_HUMAN (1-424): 0: 605: 100.00
+	At
		1257947 VPS2A_ARATH (1-221): 4.64e-58: 184: 55.16		AMSH1_ARATH (16-424): 7.05e-154: 446: 25.40
+	At
		1129495 VPS2A_ARATH (1-221): 4.64e-58: 184: 55.16		AMSH3_ARATH (16-424): 1.09e-152: 443: 29.39
+	Dm
		1360858 Q9VBI3_DROME (1-201): 3.4e-48: 160: 75.12		Q9VA71_DROME (5-424): 8.94e-156: 448: 40.41
+	Dm
		1360861 Q9VN02_DROME (4-220): 3.99e-45: 151: 22.27		Q9VA71_DROME (5-424): 8.94e-156: 448: 40.41
+	At
		1129493 VP241_ARATH (3-220): 8.53e-43: 145: 23.77		AMSH3_ARATH (16-424): 1.09e-152: 443: 29.39