HitPredict

Interactor 1: CHM2A (O43633)
Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1)
Gene: CHMP2A

Interactor 2: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 26496610, 23051622
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Snf7~Snf7
Common GO terms GO:0000421 - autophagosome membrane
GO:0000776 - kinetochore
GO:0000815 - ESCRT III complex
GO:0001778 - plasma membrane repair
GO:0005635 - nuclear envelope
and 32 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 222
Hs

1 224
+ Ce
+ At
+ Hs
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ Sc
+ At
+ At
+ Sc
+ At
+ At
+ Sc
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024