Protein: PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53) (PP1-binding protein of 114 kDa) (Phosphatase 1 nuclear targeting subunit) (Protein FB19) (p99)

Gene: PP1RA, PPP1R10
Organism: Homo sapiens
Interactions: 174
UniProt ID: Q96QC0

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0004864 - protein phosphatase inhibitor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1166710

WDR82
WD repeat-containing protein 82

2

3

Small-scale

0.825

High

726998

FUS
RNA-binding protein FUS

2

7

High-throughput

0.789

High

1084579

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

3

High-throughput

0.789

High

906092

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

11

13

Small-scale

0.760

High

737988

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

9

13

Small-scale

0.754

High

906568

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

5

13

Small-scale

0.720

High

297541

TOX4
TOX high mobility group box family member 4

4

8

Small-scale

0.699

High

446753

SNRPA
U1 small nuclear ribonucleoprotein A

1

3

High-throughput

0.691

High

1054518

RBM39
RNA-binding protein 39

1

4

High-throughput

0.691

High

1299323

RBM14
RNA-binding protein 14

1

2

High-throughput

0.691

High

1300272

RBM4B
RNA-binding protein 4B

1

3

High-throughput

0.691

High

1237975

ZFP41
Zinc finger protein 41 homolog

3

4

High-throughput

0.667

High

1300288

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

3

2

Small-scale

0.660

High

613556

SFPQ
Splicing factor, proline- and glutamine-rich

1

3

High-throughput

0.618

High

833505

RBM25
RNA-binding protein 25

1

1

High-throughput

0.618

High

1014187

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

2

High-throughput

0.618

High

1030427

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.618

High

1069769

NONO
Non-POU domain-containing octamer-binding protein

1

4

High-throughput

0.618

High

1073620

SF3B4
Splicing factor 3B subunit 4

1

3

High-throughput

0.618

High

1235779

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

2

High-throughput

0.618

High

1259860

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

2

High-throughput

0.618

High

1263509

PSPC1
Paraspeckle component 1

1

4

High-throughput

0.618

High

1300269

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

15

Small-scale

0.618

High

1300282

WDR76
WD repeat-containing protein 76

1

2

High-throughput

0.618

High

1300286

DCA13
DDB1- and CUL4-associated factor 13

1

2

High-throughput

0.618

High

1300292

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.618

High

1300293

G3BP2
Ras GTPase-activating protein-binding protein 2

1

2

High-throughput

0.618

High

508667

TOP1
DNA topoisomerase 1

2

2

High-throughput

0.611

High

1300279

FNDC4
Fibronectin type III domain-containing protein 4

3

6

High-throughput

0.609

High

1164872

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.586

High

1242567

RB15B
Putative RNA-binding protein 15B

1

0

High-throughput

0.586

High

916324

RL23A
Large ribosomal subunit protein uL23

2

0

High-throughput

0.585

High

553482

RFA2
Replication protein A 32 kDa subunit

2

2

High-throughput

0.584

High

652004

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

2

High-throughput

0.584

High

721205

RFA3
Replication protein A 14 kDa subunit

2

1

High-throughput

0.584

High

1154465

CAN13
Calpain-13

2

2

High-throughput

0.574

High

1190919

TAFA3
Chemokine-like protein TAFA-3

2

3

High-throughput

0.574

High

1235359

KCD17
BTB/POZ domain-containing protein KCTD17

2

4

High-throughput

0.574

High

1300284

MMP26
Matrix metalloproteinase-26

2

20

High-throughput

0.574

High

370243

ESR1
Estrogen receptor

2

8

High-throughput

0.571

High

1057597

RRP1B
Ribosomal RNA processing protein 1 homolog B

2

1

High-throughput

0.571

High

1074977

TERF2
Telomeric repeat-binding factor 2

2

0

Small-scale

0.569

High

124052

SPT5H
Transcription elongation factor SPT5

1

2

High-throughput

0.536

High

229971

NUAK1
NUAK family SNF1-like kinase 1

1

1

High-throughput

0.536

High

236821

CCNT1
Cyclin-T1

1

1

High-throughput

0.536

High

303430

HEXI1
Protein HEXIM1

1

1

High-throughput

0.536

High

387336

P53
Cellular tumor antigen p53

1

3

High-throughput

0.536

High

448785

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

539113

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

1

High-throughput

0.536

High

617357

SP100
Nuclear autoantigen Sp-100

1

9

High-throughput

0.536

High

791887

HD
Huntingtin

1

1

High-throughput

0.536

High

996843

SSRP1
FACT complex subunit SSRP1

1

9

High-throughput

0.536

High

1073938

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

1

High-throughput

0.536

High

1087351

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

1147775

SPT2
Protein SPT2 homolog

1

1

High-throughput

0.536

High

1160963

CTR9
RNA polymerase-associated protein CTR9 homolog

1

1

High-throughput

0.536

High

1169369

DBX2
Homeobox protein DBX2

1

7

High-throughput

0.536

High

1296360

ASPP1
Apoptosis-stimulating of p53 protein 1

1

4

High-throughput

0.536

High

1022437

TIAM1
Rho guanine nucleotide exchange factor TIAM1

2

1

High-throughput

0.521

High

1133699

RHG21
Rho GTPase-activating protein 21

2

2

High-throughput

0.521

High

207093

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

456919

FURIN
Furin

1

0

High-throughput

0.513

High

563658

ZNF24
Zinc finger protein 24

1

0

High-throughput

0.513

High

824663

MAPK2
MAP kinase-activated protein kinase 2

1

0

High-throughput

0.513

High

911937

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

985468

STP2
Nuclear transition protein 2

1

0

High-throughput

0.513

High

1205439

KMT5C
Histone-lysine N-methyltransferase KMT5C

1

0

High-throughput

0.513

High

395540

A4
Amyloid-beta precursor protein

1

10

High-throughput

0.501

High

476232

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

568767

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

3

Small-scale

0.501

High

904092

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

1

Small-scale

0.501

High

427920

CAN1
Calpain-1 catalytic subunit

1

2

High-throughput

0.489

High

949042

HTRA4
Serine protease HTRA4

1

1

High-throughput

0.489

High

1079052

CYTM
Cystatin-M

1

1

High-throughput

0.489

High

1288808

ERLEC
Endoplasmic reticulum lectin 1

1

1

High-throughput

0.489

High

962926

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.480

High

123307

CBX4
E3 SUMO-protein ligase CBX4

1

3

High-throughput

0.479

High

125659

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

228419

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

237413

CCNT2
Cyclin-T2

1

1

High-throughput

0.479

High

244813

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

263797

PR40A
Pre-mRNA-processing factor 40 homolog A

1

4

High-throughput

0.479

High

323022

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

347642

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

374724

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.479

High

398067

ISG15
Ubiquitin-like protein ISG15

1

2

High-throughput

0.479

High

445495

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.479

High

523949

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

595627

HXA5
Homeobox protein Hox-A5

1

1

High-throughput

0.479

High

632866

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.479

High

640596

DDX6
Probable ATP-dependent RNA helicase DDX6

1

2

High-throughput

0.479

High

668917

PML
Protein PML

1

2

High-throughput

0.479

High

714368

HSP74
Heat shock 70 kDa protein 4

1

3

Small-scale

0.479

High

808864

YAP1
Transcriptional coactivator YAP1

1

3

High-throughput

0.479

High

817732

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

1

High-throughput

0.479

High

822352

KC1D
Casein kinase I isoform delta

1

2

High-throughput

0.479

High

830456

KC1E
Casein kinase I isoform epsilon

1

3

High-throughput

0.479

High

841858

CDK9
Cyclin-dependent kinase 9

1

1

High-throughput

0.479

High

890806

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.479

High

917775

H4
Histone H4

1

1

High-throughput

0.479

High

952564

H33
Histone H3.3

1

2

High-throughput

0.479

High

959615

VIGLN
Vigilin

1

1

High-throughput

0.479

High

1019090

TP53B
TP53-binding protein 1

1

3

High-throughput

0.479

High

1037872

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

3

High-throughput

0.479

High

1052007

ELOA1
Elongin-A

1

3

High-throughput

0.479

High

1080255

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1188741

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1192174

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.479

High

1200588

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1221659

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

1243892

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1251810

FA76A
Protein FAM76A

1

1

High-throughput

0.479

High

1262702

ATX2L
Ataxin-2-like protein

1

4

High-throughput

0.479

High

1269407

ESR2
Estrogen receptor beta

1

8

High-throughput

0.479

High

1288569

ZBT10
Zinc finger and BTB domain-containing protein 10

1

3

Small-scale

0.479

High

1300283

ANLN
Anillin

1

2

High-throughput

0.479

High

1300287

DDX56
Probable ATP-dependent RNA helicase DDX56

1

3

High-throughput

0.479

High

1300290

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1300295

LC7L2
Putative RNA-binding protein Luc7-like 2

1

1

High-throughput

0.479

High

199809

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.458

High

204724

E41L2
Band 4.1-like protein 2

1

0

High-throughput

0.458

High

215018

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

666412

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.458

High

759785

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

848107

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

875721

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.458

High

908982

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

929348

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

941333

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1087841

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

0

High-throughput

0.458

High

1158795

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.458

High

1184277

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1189902

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1204685

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.458

High

1239265

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.458

High

1241251

FA98A
Protein FAM98A

1

0

High-throughput

0.458

High

1250991

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1300270

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1300271

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1300274

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

1300275

NUSAP
Nucleolar and spindle-associated protein 1

1

0

High-throughput

0.458

High

1300276

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.458

High

1300281

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1300285

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1300289

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1300291

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

1300294

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

101095

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

255999

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.437

High

301980

TRI37
E3 ubiquitin-protein ligase TRIM37

1

5

High-throughput

0.437

High

302690

ARHGF
Rho guanine nucleotide exchange factor 15

1

2

High-throughput

0.437

High

335166

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.437

High

385373

NTRK1
High affinity nerve growth factor receptor

1

9

High-throughput

0.437

High

536424

GLU2B
Glucosidase 2 subunit beta

1

1

High-throughput

0.437

High

1052290

SRC8
Src substrate cortactin

1

1

High-throughput

0.437

High

1126293

FA76B
Protein FAM76B

1

1

High-throughput

0.437

High

1171313

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1300278

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

928171

SUMO1
Small ubiquitin-related modifier 1

1

0

Small-scale

0.426

High

3308

A0A0S2Z547
Rho guanine nucleotide exchange factor 15 isoform 1

1

2

High-throughput

0.407

High

787295

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

2

High-throughput

0.407

High

1298024

CEP63
Centrosomal protein of 63 kDa

1

2

High-throughput

0.407

High

1300277

RSPH9
Radial spoke head protein 9 homolog

3

0

High-throughput

0.347

High

902355

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.279

Low

1174416

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.279

Low

1222452

EFC13
EF-hand calcium-binding domain-containing protein 13

1

0

High-throughput

0.279

Low

1237697

LSME1
Leucine-rich single-pass membrane protein 1

1

0

High-throughput

0.279

Low

1300296

BACE2
Beta-secretase 2

1

0

High-throughput

0.279

Low

314885

FMNL1
Formin-like protein 1

1

0

High-throughput

0.269

Low

674711

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.249

Low

1153668

ANO7
Anoctamin-7

1

0

Small-scale

0.249

Low

1300273

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.249

Low

1300280

AAMDC
Mth938 domain-containing protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024