HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: TENR (Q92752)
Tenascin-R (TN-R) (Janusin) (Restrictin)
Gene: TNR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SH2~fn3
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 1358
+	Hs
		411959 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		PTPRF_HUMAN (507-1257): 1.16e-92: 333: 14.80
+	Hs
		557632 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		DCC_HUMAN (687-1255): 7.67e-37: 154: 10.64
+	Hs
		411565 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		PTPRF_HUMAN (507-1257): 1.16e-92: 333: 14.80
+	Hs
		50508 NCK2_HUMAN (1-380): 6.88e-99: 300: 100.00		A1L306_HUMAN (8-115): 3.08e-12: 73.5: 7.97
+	Hs
		362685 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		FINC_HUMAN (125-1210): 1.31e-70: 264: 14.15
+	Hs
		616905 CSK_HUMAN (191-378): 3.44e-32: 127: 24.87		PTPRB_HUMAN (335-1025): 3.62e-58: 223: 17.62
+	Hs
		363045 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		FINC_HUMAN (125-1210): 1.31e-70: 264: 14.15
+	Hs
		362705 YES_HUMAN (6-120): 7.99e-16: 80.8: 23.08		FINC_HUMAN (125-1210): 1.31e-70: 264: 14.15
+	Mm
		56907 FYN_MOUSE (7-137): 2.1e-23: 103: 20.30		PTPRF_MOUSE (671-1263): 3.24e-57: 220: 13.20
+	Hs
		411596 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		PTPRB_HUMAN (335-1025): 3.62e-58: 223: 17.62
+	Hs
		875821 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MFAP4_HUMAN (1134-1341): 4.44e-57: 200: 46.36
+	Hs
		412016 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		PTPRD_HUMAN (416-888): 5.98e-29: 128: 14.81