Protein: SCS7
Ceramide very long chain fatty acid hydroxylase SCS7 (Ceramide VLCFA hydroxylase SCS7) (4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7) (EC 1.14.18.6) (Dihydroceramide fatty acyl 2-hydroxylase SCS7) (EC 1.14.18.7) (Sphingolipid alpha-hydroxylase) (Suppressor of calcium sensitivity 7)

Gene: SCS7
Organism: Saccharomyces cerevisiae S288C
Interactions: 50
UniProt ID: Q03529

Gene Ontology (top 5):
GO:0000038 - very long-chain fatty acid metabolic process
GO:0005506 - iron ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006631 - fatty acid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

528629

CP51
Lanosterol 14-alpha demethylase CYP51

1

5

High-throughput

0.541

High

932625

TMEDA
Endoplasmic reticulum vesicle protein 25

1

2

High-throughput

0.541

High

1043261

ERP1
Protein ERP1

1

2

High-throughput

0.541

High

797039

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.518

High

798664

SSH1
Sec sixty-one protein homolog

1

0

High-throughput

0.518

High

802013

MSC7
Putative aldehyde dehydrogenase-like protein YHR039C

1

0

High-throughput

0.518

High

823168

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.518

High

826149

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.518

High

919793

ERV29
ER-derived vesicles protein ERV29

1

0

High-throughput

0.518

High

1043262

ORM2
Protein ORM2

1

0

High-throughput

0.518

High

546080

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.504

High

916447

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

1

Small-scale

0.481

High

1043264

ATG9
Autophagy-related protein 9

1

1

Small-scale

0.479

High

914898

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.460

High

708027

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

597994

NCPR
NADPH--cytochrome P450 reductase

1

2

High-throughput

0.457

High

1035057

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.457

High

453762

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

680014

CDC48
Cell division control protein 48

1

1

High-throughput

0.445

High

646517

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.437

High

752671

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.437

High

850177

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.437

High

922111

COPA
Coatomer subunit alpha

1

1

High-throughput

0.437

High

359336

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

394858

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.407

High

486294

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.407

High

486511

TBA3
Tubulin alpha-3 chain

1

1

High-throughput

0.407

High

524985

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.407

High

527550

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.407

High

592468

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

722216

XPO1
Exportin-1

1

5

High-throughput

0.407

High

755160

GCN1
eIF-2-alpha kinase activator GCN1

1

3

High-throughput

0.407

High

816600

GEA2
ARF guanine-nucleotide exchange factor 2

1

2

High-throughput

0.407

High

817939

IMB4
Importin subunit beta-4

1

2

High-throughput

0.407

High

673026

YCT3
Uncharacterized protein YCR043C

1

0

High-throughput

0.282

High

780634

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.282

High

1043263

TGL5
Triacylglycerol lipase 5

1

0

High-throughput

0.282

High

94584

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.251

Low

435324

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.249

Low

812611

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

1043259

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

1043260

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

386840

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

427422

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

626871

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

802690

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.232

Low

835877

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.232

Low

836870

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

858056

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.232

Low

1043265

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025