HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: TTC28 (Q96AY4)
Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio)
Gene: TTC28

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 2481
+	Hs
		557767 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		TTC28_HUMAN (1-2481): 0: 1942: 100.00
+	Hs
		655282 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		PPP5_HUMAN (23-224): 1.13e-46: 178: 21.36
+	Hs
		858608 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		PPP5_HUMAN (23-224): 1.13e-46: 178: 21.36
+	Dm
		993197 GRAP_DROME (204-368): 9.19e-17: 80.1: 30.72		Q9VB22_DROME (59-448): 3.52e-36: 150: 20.51
+	Hs
		684476 CSK_HUMAN (191-378): 3.44e-32: 127: 24.87		STIP1_HUMAN (13-280): 9.62e-14: 78.7: 11.30
+	Hs
		174558 YES_HUMAN (6-120): 7.99e-16: 80.8: 23.08		OGT1_HUMAN (31-419): 2.66e-26: 120: 12.81
+	Hs
		411617 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		STIP1_HUMAN (13-280): 9.62e-14: 78.7: 11.30